Department of Paediatrics, School of Clinical Sciences at Monash Health, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Victoria, Australia.
Department of Urology, Children's Hospital at Westmead, Westmead, New South Wales, Australia.
Neurourol Urodyn. 2024 Apr;43(4):1019-1024. doi: 10.1002/nau.25450. Epub 2024 Mar 22.
Children with a neurogenic bladder are at risk of developing recurrent urinary tract infections and long-term kidney failure. Due to an altered lower urinary tract, children may be overtreated for simple bacteriuria or undertreated for a potentially severe urinary tract infection. This group of patients represent high users of healthcare, and are at risk of colonization and development of antibiotic resistance. Bladder washouts with non-antibiotic electrochemically activated solutions are a potential new prophylactic option for patients with bladder dysfunction when clean intermittent catheterization has resulted in chronic bacteriuria.
患有神经性膀胱的儿童有反复发生尿路感染和长期肾衰竭的风险。由于下尿路改变,儿童可能会因单纯菌尿而过度治疗,或因潜在严重尿路感染而治疗不足。这群患者是医疗保健的高使用者,有定植和产生抗生素耐药性的风险。对于间歇性导尿导致慢性菌尿的膀胱功能障碍患者,使用非抗生素电化学激活溶液进行膀胱冲洗可能是一种新的潜在预防选择。