Technol Health Care. 2024;32(4):2697-2709. doi: 10.3233/THC-231889.
Prosthodontics are often performed to treat patients with malocclusion and dentition defects. However, single prosthodontics cannot properly correct the disharmony of teeth, dental arch and other parts affected by malocclusion, and some patients may have difficulty in recovering the occlusal function due to poor prosthodontics.
This study aims to investigate the effect of orthodontics combined with fibre-reinforced composite resin-bonded fixed partial denture (FRC-RBFPD) on anterior dentition defects with minimal vertical intermaxillary space.
Sixty-two patients with anterior dentition defects with minimal vertical mandibular space admitted to our hospital between March 2021 and May 2023 were enrolled in this study. The participants were divided into the observation group (31 cases) and the control group (31 cases), according to the treatment plan. The control group was treated with traditional therapy, and the observation group was treated with orthodontic combined FRC-RBFPD therapy. Periodontal conditions (periodontal pocket depth [PD], the plaque index [PLI], the sulcus bleeding index [SBI]), levels of inflammatory factors in gingival crevicular fluid (high mobility group box 1 [HMGB1]), myeloid cell triggering receptor-1 (TREM-1), monocyte chemoattractant protein-1 (MCP-1), pain (visual analogue scale [VAS]), the clinical response rate and the incidence of adverse reactions were collected and compared.
After 1, 3, 5 and 9 months following treatment, the scores of the PD, PLI, SBI, HMGB1, VAS, TREM-1 and MCP-1 in the observation group were found to be lower than those in the control group (FPD treatment= 352.532, FPLI score treatment= 112.341, FSBI score treatment= 79.479, FVAS score treatment= 96.132, FHMGB1 treatment= 52.532, FTREM-1 score treatment= 64.593, FMCP-1 score treatment= 53.582, and they were all statistically significant P< 0.05). There was a statistically significant difference in the response rate between the two groups (97.77% vs. 80.65%, χ2= 4.026, P= 0.045). No statistically significant difference was observed in the incidence of adverse reactions between the two groups (6.45% vs. 16.13%, χ2= 1.449, P= 0.229).
Orthodontics combined with FRC-RBFPD shows an ideal restorative effect on patients with anterior dentition defects and minimal vertical intermaxillary space.
正颌正畸治疗常用于治疗牙列不齐和牙列缺损的患者。然而，单纯的正颌正畸治疗不能很好地纠正因牙列不齐而导致的牙齿、牙弓和其他部位的不协调，部分患者由于正颌正畸治疗效果不佳，可能难以恢复咬合功能。
本研究旨在探讨正畸联合纤维增强复合树脂粘结固定局部义齿（FRC-RBFPD）治疗前牙缺失伴最小垂直颌间距离的效果。
2021 年 3 月至 2023 年 5 月期间，我院收治了 62 例前牙缺失伴最小垂直下颌间隙的患者，将这些患者纳入本研究。根据治疗方案，将这些患者分为观察组（31 例）和对照组（31 例）。对照组患者接受传统治疗，观察组患者接受正畸联合 FRC-RBFPD 治疗。收集并比较两组患者的牙周状况（牙周袋深度[PD]、菌斑指数[PLI]、龈沟出血指数[SBI]）、龈沟液中炎症因子水平（高迁移率族蛋白 B1[HMGB1]）、髓样细胞触发受体-1（TREM-1）、单核细胞趋化蛋白-1（MCP-1）、疼痛（视觉模拟评分[VAS]）、临床疗效和不良反应发生率。
治疗后 1、3、5、9 个月，观察组患者的 PD、PLI、SBI、HMGB1、VAS、TREM-1 和 MCP-1 评分均低于对照组（FPD 治疗=352.532，FPLI 评分治疗=112.341，FSBI 评分治疗=79.479，FVAS 评分治疗=96.132，FHMGB1 治疗=52.532，FTREM-1 评分治疗=64.593，FMCP-1 评分治疗=53.582，均 P<0.05）。两组患者的临床疗效总有效率比较，差异有统计学意义（97.77%比 80.65%，χ2=4.026，P=0.045）。两组患者不良反应发生率比较，差异无统计学意义（6.45%比 16.13%，χ2=1.449，P=0.229）。
正畸联合 FRC-RBFPD 对前牙缺失伴最小垂直颌间距离的患者具有理想的修复效果。
