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经耳道-跨岩骨入路切除前庭神经鞘瘤:单中心经验。

Transcanal transpromontorial approach for vestibular schwannoma: experience of a single center.

机构信息

Section of Neurosurgery, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Italy, Ospedale Civile Maggiore Verona, Verona, Italy.

Department of Otolaryngology-Head and Neck Surgery, University Hospital of Modena, Largo del Pozzo, 71, 41125, Modena, Italy.

出版信息

Eur Arch Otorhinolaryngol. 2024 May;281(5):2679-2690. doi: 10.1007/s00405-024-08565-5. Epub 2024 Mar 22.

DOI:10.1007/s00405-024-08565-5
PMID:38519593
Abstract

BACKGROUND

The expanded transpromontorial transcanal approach (ExpTTA) represents a recent addition to the surgical approaches available for the treatment of vestibular schwannoma. An initial purely endoscopic version has been complemented by the use of the microscope and it is now one of the possible surgical options for small to medium-sized vestibular schwannomas with a predominantly intracanalar development.

METHODS

This is a series of 54 patients who underwent microsurgical resection of sporadic, unilateral vestibular schwannoma, mainly Koos I-II with non-serviceable hearing, between January 2016 and January 2023 using the expanded transcanal transpromontorial approach. We describe the surgical technique, focusing on anatomical landmarks, and analyzing its advantages and shortcomings. Retrospective analysis of clinical outcomes is presented, including early and late complications. The mean follow-up was 46.7 months.

RESULTS

We achieved gross total resection of the lesion in all cases, confirmed on the first follow-up MRI at least 6 months after each procedure. We did not record any intraoperative complication nor disease recurrence. We recorded two postoperative severe facial nerve palsies, one of which was permanent. No cases of disabling vertigo or imbalance were reported, and all patients reported full recovery of autonomy in daily activities. Three cases of otoliquorrhea were managed conservatively successfully.

CONCLUSIONS

The transcanal transpromontorial approach combines the advantages of endoscopy with the possibilities provided by microsurgery. Our experience confirms its safety in terms of surgical complications and facial nerve outcome. This approach is amongst the treatment options for small-medium schwannomas in patients with impaired hearing, especially in young patients, ensuring radical resection, disease control, and minimal morbidity.

摘要

背景

经扩大经岩前-经迷路入路(ExpTTA)是治疗前庭神经鞘瘤的一种新的手术入路。最初的纯内镜版本已经得到了显微镜的补充,现在它是治疗主要位于内听道的小至中型前庭神经鞘瘤的一种可能的手术选择之一,这些患者的听力无法保留。

方法

这是一组 54 例患者的系列病例,他们在 2016 年 1 月至 2023 年 1 月期间接受了经扩大经迷路经岩前入路显微切除术治疗单侧散发性前庭神经鞘瘤,主要为 Koos I-II 级,听力无法保留。我们描述了手术技术,重点介绍了解剖学标志,并分析了其优缺点。介绍了临床结果的回顾性分析,包括早期和晚期并发症。平均随访时间为 46.7 个月。

结果

所有病例均达到了病变的大体全切除,在每次手术后至少 6 个月的首次随访 MRI 上得到证实。我们没有记录到任何术中并发症或疾病复发。我们记录了两例术后严重面神经瘫痪,其中一例是永久性的。没有报告致残性眩晕或失衡的病例,所有患者报告在日常生活活动中完全恢复自主能力。三例耳漏成功地进行了保守治疗。

结论

经迷路经岩前入路结合了内镜的优点和显微镜手术的可能性。我们的经验证实了它在手术并发症和面神经结局方面的安全性。对于听力受损的小至中型神经鞘瘤患者,特别是年轻患者,该方法是一种治疗选择,可确保根治性切除、疾病控制和最小的发病率。

相似文献

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本文引用的文献

1
Vestibular Impairment in Patients with Vestibular Schwannoma: A Journey through the Pitfalls of Current Literature.前庭神经鞘瘤患者的前庭功能损害:探寻当前文献中的陷阱之旅
Audiol Res. 2023 Apr 13;13(2):285-303. doi: 10.3390/audiolres13020025.
2
Vestibular schwannoma removal through expanded transcanal transpromontorial approach: a multicentric experience.经扩大经耳道经鼓岬入路切除前庭神经鞘瘤:一项多中心经验
Eur Arch Otorhinolaryngol. 2023 May;280(5):2165-2172. doi: 10.1007/s00405-022-07682-3. Epub 2022 Oct 8.
3
Early Translabyrinthine Surgery for Small- and Medium-Sized Vestibular Schwannomas: Consecutive Cohort Analysis of Outcomes.
经迷路入路治疗小-中型前庭神经鞘瘤:结局的连续队列分析。
Otol Neurotol. 2022 Sep 1;43(8):962-967. doi: 10.1097/MAO.0000000000003608. Epub 2022 Aug 9.
4
What Clinicians Should Consider to Determine a More Beneficial Treatment Strategy for Small to Medium Sized Vestibular Schwannoma With Serviceable Hearing: A Single Surgeon's Long-term Outcome of Microsurgery and Gamma Knife Radiosurgery.对于具有可利用听力的中小型前庭神经鞘瘤,临床医生应考虑哪些因素来确定更有利的治疗策略:一位外科医生的显微手术和伽玛刀放射外科治疗的长期结果。
Otol Neurotol. 2020 Sep;41(8):1122-1130. doi: 10.1097/MAO.0000000000002721.
5
Hearing Restoration During Vestibular Schwannoma Surgery With Transcanal Approach: Anatomical and Functional Preliminary Report.经耳道入路听神经鞘瘤术中听力恢复:解剖学和功能初步报告。
Otol Neurotol. 2018 Dec;39(10):1304-1310. doi: 10.1097/MAO.0000000000001980.
6
Quantitative Analysis of Surgical Freedom and Area of Exposure in Minimal-Invasive Transcanal Approaches to the Lateral Skull Base.微创经耳入路侧颅底手术自由度和暴露面积的定量分析。
Otol Neurotol. 2018 Jul;39(6):785-790. doi: 10.1097/MAO.0000000000001827.
7
Intralabyrinthine schwannomas: a new surgical treatment.迷路内神经鞘瘤:一种新的手术治疗方法。
Eur Arch Otorhinolaryngol. 2018 May;275(5):1095-1102. doi: 10.1007/s00405-018-4937-0. Epub 2018 Mar 20.
8
Expanded Transcanal Transpromontorial Approach: A Novel Surgical Technique for Cerebellopontine Angle Vestibular Schwannoma Removal.扩大经耳道经岩骨入路:桥小脑角前庭神经鞘瘤切除的一种新手术技术。
Otolaryngol Head Neck Surg. 2018 Apr;158(4):710-715. doi: 10.1177/0194599818756592. Epub 2018 Feb 6.
9
Transcanal Transpromontorial Acoustic Neuroma Surgery: Results and Facial Nerve Outcomes.经耳道经鼓岬听神经瘤手术:结果与面神经预后
Otol Neurotol. 2018 Feb;39(2):242-249. doi: 10.1097/MAO.0000000000001658.
10
Comparing Outcomes Following Salvage Microsurgery in Vestibular Schwannoma Patients Failing Gamma-knife Radiosurgery or Microsurgery.比较伽玛刀放射外科手术或显微手术失败的前庭神经鞘瘤患者挽救性显微手术后的结果。
Otol Neurotol. 2017 Oct;38(9):1339-1344. doi: 10.1097/MAO.0000000000001536.