Department of Neurosurgery, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Department of Neurosurgery, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Clin Neurol Neurosurg. 2024 May;240:108252. doi: 10.1016/j.clineuro.2024.108252. Epub 2024 Mar 21.
Septated chronic subdural hematomas (cSDH) have high rates of recurrence despite surgical evacuation. Middle meningeal artery embolization (MMAE) has emerged as a promising adjuvant for secondary prevention, yet its efficacy remains ill-defined.
This is a retrospective review of septated cSDH cases treated at our institution. The surgery-only group was derived from cases performed before 2018, and the surgery+MMAE group was derived from cases performed 2018 or later. The primary outcome was reoperation rate. Secondary outcomes were recurrence, change in hematoma thickness, and midline shift.
A total of 34 cSDHs in 28 patients (surgery+MMAE) and 95 cSDHs in 83 patients (surgery-only) met the inclusion criteria. No significant difference in baseline characteristics between groups was identified. The reoperation rate was significantly higher in the surgery-only group (n = 16, 16.8%) compared with the surgery+MMAE cohort (n = 0, 0.0%) (p=0.006). A reduced incidence of recurrence (p=0.011) was also seen in the surgery+MMAE group.
MMAE for septated cSDH was found to be highly effective in preventing recurrence and reoperation. MMAE is an adjunct to surgical evacuation may be of particular benefit in this patient cohort.
尽管进行了手术清除,分隔性慢性硬脑膜下血肿(cSDH)仍有很高的复发率。脑膜中动脉栓塞(MMAE)作为二级预防的一种有前途的辅助手段已经出现,但它的疗效仍不明确。
这是对我院治疗的分隔性 cSDH 病例的回顾性研究。单纯手术组来源于 2018 年前进行的病例,手术+MMAE 组来源于 2018 年或之后进行的病例。主要结局是再次手术率。次要结局是复发、血肿厚度变化和中线移位。
共有 28 例患者(手术+MMAE)中的 34 个 cSDH 和 83 例患者(单纯手术)中的 95 个 cSDH 符合纳入标准。两组患者的基线特征无显著差异。单纯手术组的再次手术率明显高于手术+MMAE 组(n=16,16.8%)与手术+MMAE 组(n=0,0.0%)(p=0.006)。手术+MMAE 组的复发率也明显降低(p=0.011)。
MMAE 治疗分隔性 cSDH 可有效预防复发和再次手术。MMAE 是手术清除的辅助手段,可能对这类患者特别有益。