Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin; Division of Pediatric Cardiothoracic Surgery, Children's Wisconsin, Milwaukee, Wisconsin; Herma Heart Institute, Children's Wisconsin, Milwaukee, Wisconsin.
Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin; Division of Pediatric Cardiothoracic Surgery, Children's Wisconsin, Milwaukee, Wisconsin; Herma Heart Institute, Children's Wisconsin, Milwaukee, Wisconsin.
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2024;27:47-51. doi: 10.1053/j.pcsu.2024.01.007. Epub 2024 Jan 24.
The Ross procedure is an excellent option for aortic valve replacement resulting in outstanding hemodynamic performance and the ability to avoid systemic anticoagulation. The long-term durability of the autograft is generally good but concerns for later aortic root dilation with ensuing neoaortic insufficiency have prompted efforts to stabilize the autograft, root, sinuses and Sino-tubular junction in order to delay or entirely avoid late reinterventions on the neoaortic root. We have employed an inclusion technique, supporting the Auto-graft in a Terumo Gelweave™ Valsalva graft. We performed a retrospective study of all 129 patients undergoing the Ross procedure from 1992 to 2019 at Children's Wisconsin. Fifty-one underwent the supported Ross (SR) and 78 underwent unsupported Ross (UR). Structured clinical data was collected and echocardiograms were reviewed. Median follow-up was 4.9 years (up to 22.6 years) for UR patients and 3.6 years (up to 11.4 years) for SR patients. In order to provide a fair comparison, we sub -analyzed patients aged 10 to 18 years who underwent the Ross procedure, 16 who underwent the UR and 18 patients who underwent the SR. Change in aortic annulus diameter (P = 0.002), aortic sinus diameter (P = 0.001) change in left ventricular function (P = 0.039) and change in aortic insufficiency (P = 0.008) were all worse in UR. The SR is simple, reproducible, and predictable. It seems to prevent change in annulus diameter, sinus diameter and to reduce late neoaortic insufficiency. Longer follow-up with a larger group of patients is required to draw definitive conclusions.
罗斯手术是主动脉瓣置换的极佳选择,可带来出色的血液动力学性能,并能避免全身抗凝。自体移植物的长期耐久性通常较好,但由于主动脉根部扩张导致新主动脉瓣关闭不全,因此需要努力稳定自体移植物、根部、窦和窦管连接部,以延迟或完全避免新主动脉根部的晚期再介入。我们采用了一种包含技术,使用 Terumo Gelweave™ Valsalva 移植物支撑自体移植物。我们对 1992 年至 2019 年在威斯康星儿童医院接受罗斯手术的 129 例患者进行了回顾性研究。51 例患者接受了支撑性罗斯手术(SR),78 例患者接受了非支撑性罗斯手术(UR)。收集了结构化的临床数据并回顾了超声心动图。UR 患者的中位随访时间为 4.9 年(最长 22.6 年),SR 患者为 3.6 年(最长 11.4 年)。为了进行公平比较,我们对接受罗斯手术的年龄在 10 至 18 岁的患者进行了亚分析,其中 16 例接受 UR,18 例接受 SR。主动脉瓣环直径的变化(P = 0.002)、主动脉窦直径的变化(P = 0.001)、左心室功能的变化(P = 0.039)和主动脉瓣关闭不全的变化(P = 0.008)在 UR 中均更差。SR 操作简单、可重复且可预测。它似乎可以防止瓣环直径、窦直径的变化,并减少晚期新主动脉瓣关闭不全。需要更长时间的随访和更大的患者群体来得出明确的结论。