University of Sassari, Department of Medicine, Surgery and Pharmacy, Clinic of Pediatric, Sassari, Italy
University of Sassari, Department of Medicine, Surgery and Pharmacy, Clinical Epidemiology and Medical Statistics Unit, Sassari, Italy
J Clin Res Pediatr Endocrinol. 2024 Sep 5;16(3):334-339. doi: 10.4274/jcrpe.galenos.2024.2023-11-16. Epub 2024 Mar 25.
Vitamin D deficiency is a common public health issue worldwide. The purpose of this study was to investigate the vitamin D status and its potential determinants in children residing in Sardinia (40°N), Italy.
Children were enrolled over a 12-month period. Serum 25(OH)D was measured by an immunochemiluminescence assay. A questionnaire was used to gather information on other variables, including passive smoke exposure.
A total of 182 children (males: 51.7%; median age: 9 years) were included. Mean±standard deviation serum 25(OH)D was 25.2±8.3 ng/mL for the whole group. The majority (n=123, 67.6%) had vitamin D sufficient values >20 ng/mL, while 32.4% (n=59) had vitamin D insufficient/deficient values (≤20 ng/mL). Among the variables investigated, passive smoke exposure was significantly associated with insufficient 25(OH)D levels (p<0.0001).
Our results confirm that hypovitaminosis D is common in Italian children. Furthermore, passive smoke exposure was identified as a significant risk factor for hypovitaminosis D.
维生素 D 缺乏是全球常见的公共卫生问题。本研究旨在调查意大利撒丁岛（北纬 40°）儿童的维生素 D 状况及其潜在决定因素。
在 12 个月的时间内招募儿童。采用免疫化学发光法测定血清 25(OH)D。使用问卷收集其他变量的信息，包括被动吸烟暴露。
共纳入 182 名儿童（男性：51.7%；中位数年龄：9 岁）。全组血清 25(OH)D 的平均值±标准差为 25.2±8.3ng/mL。大多数（n=123，67.6%）有维生素 D 充足值>20ng/mL，而 32.4%（n=59）有维生素 D 不足/缺乏值（≤20ng/mL）。在所调查的变量中，被动吸烟暴露与 25(OH)D 水平不足显著相关（p<0.0001）。
我们的结果证实，意大利儿童普遍存在维生素 D 缺乏症。此外，被动吸烟暴露被确定为维生素 D 缺乏症的一个重要危险因素。
