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解决癌症临床试验中的差异:实现更公平入组的路线图。

Addressing disparities in cancer clinical trials: a roadmap to more equitable accrual.

作者信息

Hoin Jon A, Carthon Bradley C, Brown Shantoria J, Durham Lynn M, Garrot L Crain, Ghamande Sharad A, Pippas Andrew W, Rivers Brian M, Snyder Cindy T, Gabram-Mendola Sheryl Gordon Ann

机构信息

Rollins School of Public Health, Emory University, Atlanta, GA, United States.

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, GA, United States.

出版信息

Front Health Serv. 2024 Mar 8;4:1254294. doi: 10.3389/frhs.2024.1254294. eCollection 2024.

DOI:10.3389/frhs.2024.1254294
PMID:38523649
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10957576/
Abstract

The Georgia Center for Oncology Research and Education (Georgia CORE) and the Georgia Society of Clinical Oncology (GASCO) held a one-day summit exploring opportunities and evidence-based interventions to address disparities in cancer clinical trials. The purpose of the summit was to identify clear and concise recommendations aimed at decreasing clinical trial accrual disparities in Georgia for rural and minority populations. The summit included expert presentations, panel discussions with leaders from provider organizations throughout Georgia, and breakout sessions to allow participants to critically discuss the information presented. Over 120 participants attended the summit. Recognizing the need for evidence-based interventions to improve clinical trial accrual among rural Georgians and persons of color, summit participants identified four key areas of focus that included: improving clinical trial design, providing navigation for all, enhancing public education and awareness of cancer clinical trials, and identifying potential policy and other opportunities. A comprehensive list of takeaways and action plans was developed in the four key areas of focus with the expectation that implementation of the strategies that emerged from the summit will enhance cancer clinical trial accrual for all Georgians.

摘要

佐治亚肿瘤研究与教育中心(佐治亚CORE)和佐治亚临床肿瘤学会(GASCO)举办了一场为期一天的峰会,探讨应对癌症临床试验差异的机会和循证干预措施。峰会的目的是确定明确且简洁的建议,旨在减少佐治亚州农村和少数族裔人群在临床试验入组方面的差异。峰会内容包括专家演讲、与佐治亚州各地医疗机构领导人进行的小组讨论,以及分组会议,以便参与者深入讨论所呈现的信息。超过120人参加了此次峰会。认识到需要采取循证干预措施来提高佐治亚州农村居民和有色人种的临床试验入组率,峰会参与者确定了四个关键重点领域,包括:改进临床试验设计、为所有人提供导航、加强公众对癌症临床试验的教育和认知,以及确定潜在的政策和其他机会。在这四个关键重点领域制定了一份全面的要点和行动计划清单,期望峰会产生的策略得到实施,从而提高所有佐治亚人的癌症临床试验入组率。