Bratisl Lek Listy. 2024;125(4):264-273. doi: 10.4149/BLL_2024_40.
Medication adherence is crucial for optimal treatment outcomes, yet many patients struggle to follow their prescribed regimens, impacting patients, families, and healthcare systems. Measurement of adherence is vital for effective care planning and intervention. This review explores medication adherence challenges and measurement methods, including therapeutic drug monitoring (TDM), medication event monitoring system (MEMS), analysis of adherence in insurance/pharmacy database, pill counts, and self-reports, each with its advantages and limitations.This review advocates a partnership-based approach to adherence, stressing standardized reporting and team-based care. Adherence is influenced by many factors such as complex regimens, packaging, patient perspectives, side effects. Effectively addressing these factors is crucial for improving patient outcomes. In summary, medication adherence is vital but complex. The article covers various adherence measurement methods to promote medication adherence as an important matter (Tab. 5, Fig. 2, Ref. 91). Text in PDF www.elis.sk Keywords: medication adherence, adherence barriers, primary non-adherence, medication event monitoring system, pill count, self-report.
药物依从性对于获得最佳治疗效果至关重要,但许多患者在遵循规定的治疗方案方面存在困难,这对患者、家庭和医疗保健系统都产生了影响。对依从性进行测量对于有效的护理计划和干预至关重要。本综述探讨了药物依从性挑战和测量方法,包括治疗药物监测(TDM)、药物事件监测系统(MEMS)、保险/药房数据库中依从性分析、用药计数和自我报告,每种方法都有其优点和局限性。本综述提倡基于合作的依从性方法,强调标准化报告和团队护理。依从性受到许多因素的影响,如复杂的治疗方案、包装、患者观点、副作用等。有效解决这些因素对于改善患者结局至关重要。总之,药物依从性至关重要但也很复杂。本文涵盖了各种依从性测量方法,以促进药物依从性这一重要事项(表 5,图 2,参考文献 91)。