Xi'an Key Laboratory of C1 Compound Bioconversion Technology, School of Chemical Engineering and Technology, Xi'an Jiaotong University, Xi'an 710049, China.
Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China.
Biotechnol Adv. 2024 May-Jun;72:108347. doi: 10.1016/j.biotechadv.2024.108347. Epub 2024 Mar 23.
Mitigating greenhouse gas emissions is a critical challenge for promoting global sustainability. The utilization of CO and CH as substrates for the production of valuable products offers a promising avenue for establishing an eco-friendly economy. Biocatalysis, a sustainable process utilizing enzymes to facilitate biochemical reactions, plays a significant role in upcycling greenhouse gases. This review provides a comprehensive overview of the enzymes and associated reactions involved in the biocatalytic conversion of CO and CH. Furthermore, the challenges facing the field are discussed, paving the way for future research directions focused on developing robust enzymes and systems for the efficient fixation of CO and CH.
减轻温室气体排放是促进全球可持续性发展的关键挑战。利用 CO 和 CH 作为生产有价值产品的底物为建立环保型经济提供了一个有前途的途径。生物催化是一种利用酶促进生化反应的可持续过程，在温室气体的升级利用中发挥着重要作用。本文综述了 CO 和 CH 的生物催化转化中涉及的酶及相关反应，讨论了该领域面临的挑战，为未来的研究方向铺平了道路，重点是开发用于 CO 和 CH 高效固定的稳健酶和系统。
