Department of Neurology, University of Health Sciences Adana City Training and Research Hospital, Adana, Turkey.
Department of Neurology, Division of Clinical Neurophysiology, University of Health Sciences Adana City Training and Research Hospital, Adana, Turkey.
Niger J Clin Pract. 2024 Mar 1;27(3):345-351. doi: 10.4103/njcp.njcp_461_22. Epub 2024 Mar 26.
It is not yet clear if gravidity and parity have any relationships with the electrodiagnostic parameters of carpal tunnel syndrome (CTS).
To determine whether there is a relationship between electrodiagnostic findings, gravidity, and parity number in CTS.
Female patients over 18 years of age with CTS were included in this retrospective cohort study. The gravidity/parity number, median nerve compound muscle action potential (CMAP), and compound nerve action potential (CNAP) of the patients were analyzed. The two subgroups of the Boston carpal tunnel syndrome questionnaire (BCTSQ): The Symptom Severity Scale (SSS) and Functional Severity Scale (FSS) were applied to the patients. CTS patients were divided into two groups aged at first pregnancy ≤20 years and >20 years.
One hundred and eight CTS extremities (seven right-sided CTS, three left-sided CTS, 49 bilateral CTS) of 59 patients were included. The median (interquartile range: 25%-75%) number of gravidity, parity, and abortion were 3 (2-5), 3 (2-4), and 0 (0-0), respectively. Right-sided CTS patients at the age of first pregnancy ≤20 years had higher BCTSQ-SSS/FSS scores and median nerve CMAP latency compared to patients at the age of first pregnancy >20 years (P = 0.029 for SSS; P = 0.042 for FSS; and P = 0.041 for CMAP latency). A negative correlation was found between the gravidity/parity numbers and median nerve CNAP/CMAP amplitudes (P = 0.028/0.031, r = -0.293/-0.289 for CNAP amplitude; and P = 0.006/0.035, r = -0.363/-0.283 for CMAP amplitude).
Neurophysiological findings worsen as the number of gravidity and parity increase. Electrodiagnostic and clinical features of CTS may be worsening in females below 20 years at first pregnancy.
目前尚不清楚妊娠和分娩次数是否与腕管综合征（CTS）的电诊断参数有关。
确定 CTS 患者的电诊断结果、妊娠和分娩次数之间是否存在关系。
本回顾性队列研究纳入了年龄在 18 岁以上的 CTS 女性患者。分析了患者的妊娠/分娩次数、正中神经复合肌肉动作电位（CMAP）和复合神经动作电位（CNAP）。应用波士顿腕管综合征问卷（BCTSQ）的两个亚量表：症状严重程度量表（SSS）和功能严重程度量表（FSS）对患者进行评估。将 CTS 患者分为初孕年龄≤20 岁和>20 岁两个亚组。
纳入了 59 例患者的 108 侧 CTS 肢体（7 例右侧 CTS、3 例左侧 CTS、49 例双侧 CTS）。妊娠（中位数[四分位数范围 25%-75%]）、分娩和流产的中位数（范围）分别为 3（2-5）、3（2-4）和 0（0-0）。初孕年龄≤20 岁的右侧 CTS 患者的 BCTSQ-SSS/FSS 评分和正中神经 CMAP 潜伏期均高于初孕年龄>20 岁的患者（SSS：P=0.029；FSS：P=0.042；CMAP 潜伏期：P=0.041）。妊娠/分娩次数与正中神经 CNAP/CMAP 振幅呈负相关（CNAP 振幅：P=0.028/0.031，r=-0.293/-0.289；CMAP 振幅：P=0.006/0.035，r=-0.363/-0.283）。
妊娠和分娩次数的增加会导致神经生理学结果恶化。初孕年龄<20 岁的女性 CTS 患者的电诊断和临床特征可能会恶化。
