Department of Endocrinology, Hospital Infantil Universitario Niño Jesús, Instituto de Investigación La Princesa, Madrid, Spain.
Department of Pediatrics, Faculty of Medicine, Universidad Autónoma de Madrid, Madrid, Spain.
Physiology (Bethesda). 2024 Jul 1;39(4):0. doi: 10.1152/physiol.00009.2024. Epub 2024 Mar 26.
Astrocytes are no longer considered as passive support cells. In the hypothalamus, these glial cells actively participate in the control of appetite, energy expenditure, and the processes leading to obesity and its secondary complications. Here we briefly review studies supporting this conclusion and the advances made in understanding the underlying mechanisms.
星形胶质细胞不再被认为是被动的支持细胞。在下丘脑，这些神经胶质细胞积极参与食欲、能量消耗以及导致肥胖及其继发并发症的过程的控制。在这里，我们简要回顾支持这一结论的研究以及在理解潜在机制方面取得的进展。
