Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Amsterdam Public Health Research Institute, Amsterdam University Medical Centres, Amsterdam, The Netherlands.
Psychol Med. 2024 Jul;54(10):2572-2584. doi: 10.1017/S0033291724000692. Epub 2024 Mar 27.
Wellbeing is relatively stable over the life span. However, individuals differ in this stability and change. One explanation for these differences could be the influence of different genetic or environmental factors on wellbeing over time.
To investigate causes of stability and change of wellbeing across the lifespan, we used cohort-sequential data on wellbeing from twins and their siblings of the Netherlands Twin Register (NTR) (total = 46.885, 56% females). We organized wellbeing data in multiple age groups, from childhood (age 5), to adolescence, up to old age (age 61+). Applying a longitudinal genetic simplex model, we investigated the phenotypic stability of wellbeing and continuity and change in genetic and environmental influences.
Wellbeing peaked in childhood, decreased during adolescence, and stabilized during adulthood. In childhood and adolescence, around 40% of the individual differences was explained by genetic effects. The heritability decreased toward old adulthood (35-24%) and the contribution of unique environmental effects increased to 76%. Environmental innovation was found at every age, whereas genetic innovation was only observed during adolescence (10-18 years). In childhood and adulthood, the absence of genetic innovation indicates a stable underlying set of genes influencing wellbeing during these life phases.
These findings provide insights into the stability and change of wellbeing and the genetic and environmental influences across the lifespan. Genetic effects were mostly stable, except in adolescence, whereas the environmental innovation at every age suggests that changing environmental factors are a source of changes in individual differences in wellbeing over time.
幸福感在整个生命周期中相对稳定。然而,个体在这种稳定性和变化上存在差异。这些差异的一个解释可能是不同的遗传或环境因素随着时间的推移对幸福感的影响。
为了探究幸福感在整个生命周期中稳定性和变化的原因,我们使用了荷兰双胞胎登记处(NTR)双胞胎及其兄弟姐妹的队列序列幸福感数据(共 46885 人,女性占 56%)。我们将幸福感数据组织成多个年龄组,从儿童期(5 岁)到青春期,再到老年期(61 岁及以上)。应用纵向遗传单体模型,我们研究了幸福感的表型稳定性以及遗传和环境影响的连续性和变化。
幸福感在儿童期达到峰值,在青春期下降,在成年期稳定。在儿童期和青春期,约 40%的个体差异由遗传效应解释。遗传性在成年后期(35-24%)下降,独特环境效应的贡献增加到 76%。在每个年龄段都发现了环境创新,而遗传创新仅在青春期(10-18 岁)观察到。在儿童期和成年期,缺乏遗传创新表明,在这些生命阶段,有一组稳定的潜在基因影响幸福感。
这些发现提供了幸福感稳定性和变化以及遗传和环境影响的深入了解。遗传效应大多是稳定的,除了在青春期,而每个年龄段的环境创新表明,随着时间的推移,不断变化的环境因素是幸福感个体差异变化的一个来源。