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用于无导线房室同步起搏的新型心房机械感知方法的可行性。

Feasibility of a novel atrial mechanical sensing method for leadless atrioventricular synchronous pacing.

机构信息

Department of Cardiology, Tokyo Medical University Hachioji Medical Center, Tokyo, Japan.

Department of Cardiology, Tokyo Medical University Hospital, Tokyo, Japan.

出版信息

J Cardiovasc Electrophysiol. 2024 Jun;35(6):1115-1120. doi: 10.1111/jce.16255. Epub 2024 Mar 27.

Abstract

INTRODUCTION

Few studies have demonstrated a high degree of atrioventricular (AV) synchrony with a new leadless pacemaker called Micra AV. Our group previously reported a new and unique sensing method. We believe that this novel sensing method, "Simplified A3 method," might facilitate better AV synchrony than a conventional sensing method in almost all cases with Micra AV implantation.

METHODS

We conducted a non-randomized retrospective study comparing the two pacing methods at two centers. From December 1, 2021 to October 31, 2022, Micra AV was implanted for 32 patients at the two centers. Twenty of the 32 patients with sinus rhythm and complete AV block were included in this study. In Group 1, the conventional setting was programmed as follows: auto A3 threshold, auto A3 window-end (WE), and auto A4 threshold turned on during hospitalization. In Group 2, the "Simplified A3 method" was programmed as follows: auto A3 threshold and auto A3WE turned off. Instead, an intentionally prolonged A3WE (850-1000 ms) and low A3 threshold (A3 signal amplitude + 0.5-1.0 m/s) were programmed.

RESULTS

Twenty patients were analyzed. In Group 2, AV synchrony (%AMVp) was significantly higher at the first outpatient clinic (63.0 ± 5.7% vs 81.0 ± 4.2%, p = .03). A3 threshold was significantly lower in Group 2 (5.9 ± 0.7 m/s, p < .05 vs 2.3 ± 0.5 m/s, p < .05).

CONCLUSION

Our novel sensing method might be a more feasible sensing method for obtaining higher AV synchrony than the conventional algorithm.

摘要

引言

鲜有研究证明新型无导线起搏器 Micra AV 具有高度的房室(AV)同步性。我们的团队此前报告了一种新的独特感知方法。我们认为,这种新的感知方法“简化 A3 方法”在几乎所有植入 Micra AV 的情况下,都可能比传统感知方法更有助于实现更好的 AV 同步性。

方法

我们在两个中心进行了一项非随机回顾性研究,比较了两种起搏方法。2021 年 12 月 1 日至 2022 年 10 月 31 日,两个中心共植入 32 例 Micra AV,其中 20 例窦性节律伴完全 AV 阻滞的患者纳入本研究。在第 1 组中,将常规设置编程为以下内容:自动 A3 阈值、自动 A3 窗口末端(WE)和自动 A4 阈值在住院期间开启。在第 2 组中,采用“简化 A3 方法”编程,即自动 A3 阈值和自动 A3WE 关闭。相反,故意延长 A3WE(850-1000ms)并降低 A3 阈值(A3 信号幅度+0.5-1.0m/s)。

结果

共分析了 20 例患者。在第 2 组中,第 1 次门诊时 AV 同步性(%AMVp)显著更高(63.0±5.7% vs 81.0±4.2%,p=0.03)。第 2 组 A3 阈值明显更低(5.9±0.7m/s,p<0.05 vs 2.3±0.5m/s,p<0.05)。

结论

我们的新感知方法可能是一种比传统算法更可行的获得更高 AV 同步性的感知方法。

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