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在上颌前牙区牙槽嵴保存后植入种植体的长期美学和影像学效果:牛异种移植物与胶原基质联合应用

The Long-Term Esthetic and Radiographic Outcome of Implants Placed in the Anterior Maxilla after Ridge Preservation, Combining Bovine Xenograft with Collagen Matrix.

作者信息

Batas Leonidas, Xanthopoulou Vithleem, Gnigou Maria, Vagdouti Triantafyllia, Fragkioudakis Ioannis, Vouros Ioannis

机构信息

Department of Preventive Dentistry, Periodontology and Implant Biology, School of Dentistry, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.

出版信息

Dent J (Basel). 2024 Mar 20;12(3):80. doi: 10.3390/dj12030080.

DOI:10.3390/dj12030080
PMID:38534304
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10968737/
Abstract

The objective of the study was to evaluate the long-term esthetic and radiographic results of implants placed in the anterior maxilla after ridge preservation, combining bovine xenograft with collagen matrix. Fifteen patients who required a single tooth extraction because of fracture, root resorption, or extended caries were included in the study. After extraction, all sites were grafted using Deproteinized Bovine Bone Mineral (DBBM) with collagen and covered by a resorbable collagen matrix (CM). Five months after socket grafting, implants were successfully installed. The implant diameter range was between 3.8 and 4.2 mm. All patients were monitored for over 7 years, both clinically and radiographically. Three independent observers evaluated the long-term esthetic outcome, employing the Pink Esthetic Score (PES) technique. Over a period exceeding seven years, a 100% survival rate was observed for all 15 implants, with minimal marginal bone loss. The mean PES was 11.40 (±1.44) at the first assessment and 11.38 (±1.63) at the second assessment. The difference was not statistically significant ( = 0.978), and the scores of PES measurements indicated excellent esthetic results even after seven years. Based on these preliminary results, it seems that placing collagen bovine bone in a fresh extraction socket, covered with a collagen matrix, can preserve the alveolar ridge and provide long-term stable esthetic results.

摘要

本研究的目的是评估在前上颌骨进行牙槽嵴保存后植入种植体的长期美学和影像学效果,将牛异种移植物与胶原基质相结合。15名因骨折、牙根吸收或严重龋齿而需要拔除单颗牙齿的患者纳入本研究。拔牙后,所有位点均使用脱蛋白牛骨矿物质(DBBM)与胶原进行植骨,并覆盖可吸收胶原基质(CM)。牙槽窝植骨5个月后,成功植入种植体。种植体直径范围在3.8至4.2毫米之间。所有患者均接受了超过7年的临床和影像学监测。三名独立观察者采用粉色美学评分(PES)技术评估长期美学效果。在超过七年的时间里,观察到所有15颗种植体的存活率为100%,边缘骨丢失极少。首次评估时的平均PES为11.40(±1.44),第二次评估时为11.38(±1.63)。差异无统计学意义(P = 0.978),即使在七年之后,PES测量得分也表明美学效果极佳。基于这些初步结果,似乎将胶原牛骨置于新鲜拔牙窝内并覆盖胶原基质,可以保存牙槽嵴并提供长期稳定的美学效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a902/10968737/f2427f6be17e/dentistry-12-00080-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a902/10968737/cab4efe9a963/dentistry-12-00080-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a902/10968737/c963fa33643f/dentistry-12-00080-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a902/10968737/20983d80c5ee/dentistry-12-00080-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a902/10968737/0ba3e8eeea7b/dentistry-12-00080-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a902/10968737/60122dd98a6f/dentistry-12-00080-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a902/10968737/941ee4806d81/dentistry-12-00080-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a902/10968737/f2427f6be17e/dentistry-12-00080-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a902/10968737/cab4efe9a963/dentistry-12-00080-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a902/10968737/c963fa33643f/dentistry-12-00080-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a902/10968737/20983d80c5ee/dentistry-12-00080-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a902/10968737/0ba3e8eeea7b/dentistry-12-00080-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a902/10968737/60122dd98a6f/dentistry-12-00080-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a902/10968737/941ee4806d81/dentistry-12-00080-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a902/10968737/f2427f6be17e/dentistry-12-00080-g007.jpg

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本文引用的文献

1
Extraction Socket Augmentation with Autologous Platelet-Rich Fibrin (PRF): The Rationale for Socket Augmentation.自体富血小板纤维蛋白(PRF)用于拔牙窝骨增量:拔牙窝骨增量的理论依据
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Hard and soft tissue evaluation of alveolar ridge preservation compared to spontaneous healing: a retrospective clinical and volumetric analysis.比较牙槽嵴保存与自发愈合的硬组织和软组织评估:回顾性临床和体积分析。
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Soft tissue augmentation with a volume-stable collagen matrix or an autogenous connective tissue graft at implant sites: Five-year results of a randomized controlled trial post implant loading.
在种植体植入部位使用体积稳定的胶原基质或自体结缔组织移植物进行软组织增量:种植体加载后随机对照试验的五年结果
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Three-Dimensional Volumetric Changes After Socket Augmentation with Deproteinized Bovine Bone and Collagen Matrix.脱蛋白牛骨和胶原基质进行牙槽窝骨增量后的三维容积变化。
Int J Oral Maxillofac Implants. 2020 May/Jun;35(3):566-575. doi: 10.11607/jomi.7961.
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The Influence of Different Grafting Materials on Alveolar Ridge Preservation: a Systematic Review.不同移植材料对牙槽嵴保存的影响:一项系统评价
J Oral Maxillofac Res. 2019 Sep 5;10(3):e6. doi: 10.5037/jomr.2019.10306. eCollection 2019 Jul-Sep.
8
Extracellular matrix-based scaffolding technologies for periodontal and peri-implant soft tissue regeneration.基于细胞外基质的支架技术在牙周和种植体周围软组织再生中的应用。
J Periodontol. 2020 Jan;91(1):17-25. doi: 10.1002/JPER.19-0351. Epub 2019 Sep 19.
9
Dimensional changes following alveolar ridge preservation in the posterior area using bovine-derived xenografts and collagen membrane compared to spontaneous healing: a 6-month randomized controlled clinical trial.采用牛源性异种移植物和胶原膜行牙槽嵴保存后,与自发愈合相比,后牙区的牙槽嵴尺寸变化:一项 6 个月的随机对照临床试验。
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The effectiveness of immediate implant placement for single tooth replacement compared to delayed implant placement: A systematic review and meta-analysis.即刻种植与延期种植在单牙缺失修复中效果的比较:系统评价和 Meta 分析。
J Clin Periodontol. 2019 Jun;46 Suppl 21:224-241. doi: 10.1111/jcpe.13054.