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使用双模态深度神经网络进行自主心脏B分割在高场心脏磁共振成像中的可靠失谐校正

Reliable Off-Resonance Correction in High-Field Cardiac MRI Using Autonomous Cardiac B Segmentation with Dual-Modality Deep Neural Networks.

作者信息

Li Xinqi, Huang Yuheng, Malagi Archana, Yang Chia-Chi, Yoosefian Ghazal, Huang Li-Ting, Tang Eric, Gao Chang, Han Fei, Bi Xiaoming, Ku Min-Chi, Yang Hsin-Jung, Han Hui

机构信息

Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin, Germany.

出版信息

Bioengineering (Basel). 2024 Feb 23;11(3):210. doi: 10.3390/bioengineering11030210.

Abstract

B0 field inhomogeneity is a long-lasting issue for Cardiac MRI (CMR) in high-field (3T and above) scanners. The inhomogeneous B0 fields can lead to corrupted image quality, prolonged scan time, and false diagnosis. B0 shimming is the most straightforward way to improve the B0 homogeneity. However, today's standard cardiac shimming protocol requires manual selection of a shim volume, which often falsely includes regions with large B0 deviation (e.g., liver, fat, and chest wall). The flawed shim field compromises the reliability of high-field CMR protocols, which significantly reduces the scan efficiency and hinders its wider clinical adoption. This study aims to develop a dual-channel deep learning model that can reliably contour the cardiac region for B0 shim without human interaction and under variable imaging protocols. By utilizing both the magnitude and phase information, the model achieved a high segmentation accuracy in the B0 field maps compared to the conventional single-channel methods (Dice score: 2D-mag = 0.866, 3D-mag = 0.907, and 3D-mag-phase = 0.938, all < 0.05). Furthermore, it shows better generalizability against the common variations in MRI imaging parameters and enables significantly improved B0 shim compared to the standard method (SD(B0Shim): Proposed = 15 ± 11% vs. Standard = 6 ± 12%, < 0.05). The proposed autonomous model can boost the reliability of cardiac shimming at 3T and serve as the foundation for more reliable and efficient high-field CMR imaging in clinical routines.

摘要

对于高场强(3T及以上)扫描仪中的心脏磁共振成像(CMR)而言,B0场不均匀性是一个长期存在的问题。不均匀的B0场会导致图像质量受损、扫描时间延长以及误诊。B0匀场是改善B0均匀性的最直接方法。然而,当今的标准心脏匀场方案需要手动选择匀场体积,这常常错误地包含了B0偏差较大的区域(如肝脏、脂肪和胸壁)。有缺陷的匀场会影响高场CMR方案的可靠性,显著降低扫描效率,并阻碍其在临床上更广泛的应用。本研究旨在开发一种双通道深度学习模型,该模型能够在无人工干预且成像方案可变的情况下,可靠地勾勒出用于B0匀场的心脏区域。通过同时利用幅度和相位信息,与传统单通道方法相比,该模型在B0场图中实现了较高的分割精度(Dice分数:二维幅度=0.866,三维幅度=0.907,三维幅度-相位=0.938,均P<0.05)。此外,与标准方法相比,该模型在MRI成像参数常见变化方面具有更好的通用性,并且能够显著改善B0匀场(B0匀场标准差:所提方法=15±11%,标准方法=6±12%,P<0.05)。所提出的自主模型可以提高3T时心脏匀场的可靠性,并为临床常规中更可靠、高效的高场CMR成像奠定基础。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8f1/10968050/2421023cbcc5/bioengineering-11-00210-g001.jpg

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