Siebes M, D'Argenio D Z, Selzer R H
Comput Methods Programs Biomed. 1985 Nov;21(2):143-52. doi: 10.1016/0169-2607(85)90075-6.
A computer-assisted analysis of coronary obstructions from cineangiograms is presented, which includes both the geometric and hemodynamic evaluation of coronary stenosis severity. Single frame images are digitized into a 512 X 512 X 8 bit array after a cine-to-video conversion. Automatic edge tracking is performed using a combination of derivative and threshold methods. Vessel borders from two orthogonal views of the arterial segment are used to create a three-dimensional reconstruction of the stenosis, which serves as a basis for calculation of absolute and relative geometric dimensions, stenotic resistance and trans-stenotic pressure gradient for various given flow rates. A preliminary performance evaluation of this method was made by analysis of x-ray phantoms representing stenoses of known dimensions, which were filmed under quasi-clinical conditions. The results are discussed with respect to their accuracy and reproducibility.
本文介绍了一种对心血管造影术中冠状动脉阻塞进行计算机辅助分析的方法，该方法包括对冠状动脉狭窄严重程度的几何和血流动力学评估。在将电影血管造影转换为视频后，单帧图像被数字化为一个512×512×8位的数组。使用导数和阈值方法相结合的方式进行自动边缘跟踪。动脉段两个正交视图的血管边界用于创建狭窄的三维重建，这为计算各种给定流速下的绝对和相对几何尺寸、狭窄阻力和跨狭窄压力梯度奠定了基础。通过分析在准临床条件下拍摄的代表已知尺寸狭窄的X射线模型，对该方法进行了初步性能评估。讨论了结果的准确性和可重复性。
