Zubkov Mikhail O, Dilman Alexander D
N. D. Zelinsky Institute of Organic Chemistry, Leninsky prosp. 47, 119991 Moscow, Russian Federation.
Chem Soc Rev. 2024 May 7;53(9):4741-4785. doi: 10.1039/d3cs00889d.
Polyfluoroarenes have been known for a long time, but they are most often used as fluorinated building blocks for the synthesis of aromatic compounds. At the same time, due to peculiar fluorine effect, they have unique properties that provide applications in various fields ranging from synthesis to materials science. This review summarizes advances in the radical chemistry of polyfluoroarenes, which have become possible mainly with the advent of photocatalysis. Transformations of the fluorinated ring the C-F bond activation, as well as use of fluoroaryl fragments as activating groups and hydrogen atom transfer agents are discussed. The ability of fluoroarenes to serve as catalysts is also considred.
多氟芳烃早已为人所知，但它们最常被用作合成芳香族化合物的氟化砌块。同时，由于独特的氟效应，它们具有独特的性质，在从合成到材料科学的各个领域都有应用。本综述总结了多氟芳烃自由基化学的进展，这主要随着光催化的出现而成为可能。讨论了氟化环的转化、C-F键活化，以及氟芳基片段作为活化基团和氢原子转移剂的用途。还考虑了氟芳烃作为催化剂的能力。
