AORN J. 2024 Apr;119(4):261-274. doi: 10.1002/aorn.14111.
Many surgeons request use of 10% povidone-iodine (PI) for vaginal antisepsis; however, when PI is contraindicated, some surgeons request use of chlorhexidine gluconate (CHG) instead. The purpose of this randomized controlled trial was to determine any significant differences in self-reported symptoms associated with vaginal antisepsis with either 10% PI scrub or 4% CHG with 4% isopropyl alcohol. The control group comprised 62 participants who underwent vaginal antisepsis with the PI product, and the intervention group comprised 58 participants who underwent vaginal antisepsis with the CHG product. Participants completed surveys immediately before surgery, immediately after surgery, and 48 to 72 hours after surgery. No significant differences were found in the reported vaginal symptoms between the two groups for any survey. One participant in the intervention group reported symptoms consistent with an allergic reaction. Additional studies are needed on the use of CHG for vaginal antisepsis.
许多外科医生要求使用 10%聚维酮碘（PI）进行阴道消毒；然而，当 PI 被禁忌时，一些外科医生要求使用葡萄糖酸洗必泰（CHG）代替。本随机对照试验的目的是确定使用 10%PI 擦洗或 4%CHG 加 4%异丙醇进行阴道消毒与阴道消毒相关的自我报告症状是否存在任何显著差异。对照组由 62 名接受 PI 产品阴道消毒的参与者组成，干预组由 58 名接受 CHG 产品阴道消毒的参与者组成。参与者在手术前、手术后立即以及手术后 48 至 72 小时完成了调查。在任何调查中，两组报告的阴道症状均无显著差异。干预组的一名参与者报告了与过敏反应一致的症状。需要进一步研究 CHG 用于阴道消毒的情况。
