Key Laboratory of Carbohydrate Science and Engineering, Chongqing Key Laboratory of Inorganic Functional Materials, Chongqing Normal University, Chongqing 401331, China.
Food Funct. 2024 Apr 22;15(8):3939-3958. doi: 10.1039/d3fo05747j.
The mulberry plant is a member of the Moraceae family and belongs to the genus. Its entire body is a treasure, with mulberries, mulberry leaves, and mulberry branches all suitable for medicinal use. The main active ingredient in mulberries is mulberry polysaccharide. Studies have shown that polysaccharides from different parts of mulberry exhibit antioxidant, antidiabetic, antibacterial, anti-inflammatory, and blood pressure-lowering properties. There are more studies on the biological activities, extraction methods, and structural characterization of polysaccharides from different parts of mulberry. However, the structural characterization of mulberry polysaccharides is mostly confined to the types and proportions of monosaccharides and the molecular weights of polysaccharides, and there are fewer systematic studies on polysaccharides from different parts of mulberry. In order to better understand the bioactive structure of mulberry polysaccharides, this article discusses the recent research progress in the extraction, separation, purification, bioactivity, structural modification, and application of polysaccharides from different parts of mulberry (mulberry leaves, mulberry fruits, and mulberry branches). It also delves into the pharmacological mechanisms of action of mulberry polysaccharides to provide a theoretical basis for further research on mulberry polysaccharides with a view to their deeper application in the fields of feed and nutraceuticals.
桑树是桑科植物的一员,属于桑属。它的全身都是宝,桑葚、桑叶、桑枝都可入药。桑树的主要活性成分是桑多糖。研究表明,不同部位的桑多糖具有抗氧化、降血糖、抗菌、抗炎、降血压等作用。对不同部位桑多糖的生物活性、提取方法和结构特征已有较多研究。然而,桑多糖的结构特征大多局限于单糖的种类和比例以及多糖的分子量,对不同部位桑多糖的系统研究较少。为了更好地了解桑多糖的生物活性结构,本文综述了不同部位(桑叶、桑果、桑枝)桑多糖的提取、分离、纯化、生物活性、结构修饰及应用的最新研究进展,并探讨了桑多糖的药理作用机制,为进一步研究桑多糖提供理论依据,以期在饲料和营养保健品领域得到更深入的应用。