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社区军队医院的感染性动脉炎及其处理。

Infectious aortitis and managing it at a community military hospital.

机构信息

General Surgery, William Beaumont Army Medical Center, El Paso, Texas, USA.

General Surgery, William Beaumont Army Medical Center, El Paso, Texas, USA

出版信息

BMJ Case Rep. 2024 Mar 27;17(3):e257509. doi: 10.1136/bcr-2023-257509.

DOI:10.1136/bcr-2023-257509
PMID:38538095
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10982747/
Abstract

Infectious aortitis is a rare disease process which can be of fungal, viral or bacterial aetiology. This disease process is often incidentally found during concomitant infectious processes, likely due to haematogenous spread. Common sources are from cardiac, genitourinary and gastroenterologic sources. CT imaging of the aorta is essential in identifying physiological changes-wall thickness changes, ectasia and stenosis. We present a case of a female in her early 60s with a medical history of cardiomyopathy with heart failure and reduced ejection fraction, who was initially admitted for acute cholecystitis complicated by the development of gallstone pancreatitis. Imaging evaluation incidentally noted findings consistent with aortitis with a penetrating ulcer, and blood cultures were positive for bacteraemia, confirming her diagnosis of infectious aortitis. She was started on intravenous antibiotics, required preoperative nutritional optimisation, and subsequently underwent an open aortic resection and aortoiliac reconstruction with rifampin-soaked Dacron graft.

摘要

感染性动脉炎是一种罕见的疾病过程,可由真菌、病毒或细菌引起。这种疾病过程通常是在伴随的感染过程中偶然发现的,可能是由于血源性播散所致。常见的来源是心脏、泌尿生殖和胃肠来源。主动脉的 CT 成像对于识别生理变化-壁厚度变化、扩张和狭窄至关重要。我们报告了一位 60 多岁女性的病例,她有心肌病伴心力衰竭和射血分数降低的病史,最初因急性胆囊炎并发胆石性胰腺炎入院。影像学评估偶然发现了符合穿透性溃疡的动脉炎的表现,血培养阳性为菌血症,证实了她感染性动脉炎的诊断。她开始接受静脉注射抗生素治疗,需要术前营养优化,随后接受了开放式主动脉切除术和腹主动脉-髂动脉重建术,使用利福平浸泡的涤纶移植物。

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本文引用的文献

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2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines.2022 ACC/AHA 血管疾病诊断与管理指南:美国心脏协会/美国心脏病学会联合临床实践指南委员会的报告。
Circulation. 2022 Dec 13;146(24):e334-e482. doi: 10.1161/CIR.0000000000001106. Epub 2022 Nov 2.
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Retrospective Multicenter Study Comparing Infectious and Noninfectious Aortitis.比较感染性与非感染性主动脉炎的回顾性多中心研究
Clin Infect Dis. 2023 Feb 8;76(3):e1369-e1378. doi: 10.1093/cid/ciac560.
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Infectious Aortitis: Case Report and Literature Review.感染性主动脉炎:病例报告及文献综述
Cureus. 2022 Mar 15;14(3):e23198. doi: 10.7759/cureus.23198. eCollection 2022 Mar.
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Aortitis: recent advances, current concepts and future possibilities.主动脉炎:最新进展、现有概念和未来可能。
Heart. 2021 Oct;107(20):1620-1629. doi: 10.1136/heartjnl-2020-318085. Epub 2021 Feb 16.
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Aortitis - An Interdisciplinary Challenge.主动脉炎:跨学科的挑战
In Vivo. 2021 Jan-Feb;35(1):41-52. doi: 10.21873/invivo.12230.
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A strobe multicenter descriptive study of 55 infectious aortitis.一项对55例感染性主动脉炎的频闪多中心描述性研究。
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Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology: I. Inflammatory diseases.心血管病理学会和欧洲心血管病理协会关于主动脉外科病理学的共识声明:I. 炎症性疾病。
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