Martino Cinnera Alex, Verna Valeria, Marucci Matteo, Tavernese Aurora, Magnotti Luisa, Matano Alessandro, D'Acunto Chiara, Paolucci Stefano, Morone Giovanni, Betti Viviana, Tramontano Marco
IRCCS Santa Lucia Foundation, 00179 Rome, Italy.
Braintrends Limited, Applied Neuroscience, 00192 Rome, Italy.
Brain Sci. 2024 Mar 15;14(3):283. doi: 10.3390/brainsci14030283.
About one-third of stroke survivors present unilateral spatial neglect (USN) that negatively impacts the rehabilitation outcome. We reported the study protocol and usability results of an eye-tracking (ET) biofeedback immersive virtual reality (iVR) protocol. Healthy controls and stroke patients with and without USN underwent a single session of the three iVR tasks. The system usability scale (SUS), adverse events (AEs), and ET data were collected and analyzed via parametric analysis. Twelve healthy controls (six young adults and six older adults) and seven patients with a diagnosis of single ischemic stroke (four without USN and three with confirmed diagnosis of USN) completed the usability investigation. SUS results showed good acceptability of the system for healthy controls and stroke patients without USN. ET results showed a lower performance for patients with USN concerning healthy controls and stroke patients without USN, in particular in the exploration of the left visual field. The results showed that the proposed iVR-ET biofeedback protocol is a safe and well-tolerated technique in patients with USN. The real-time feedback can induce a performance response supporting its investigation such as a treatment approach.
约三分之一的中风幸存者存在单侧空间忽视（USN），这对康复结果产生负面影响。我们报告了一项眼动追踪（ET）生物反馈沉浸式虚拟现实（iVR）方案的研究方案及可用性结果。有或没有USN的健康对照者以及中风患者接受了一次包含三项iVR任务的实验。通过参数分析收集并分析了系统可用性量表（SUS）、不良事件（AE）和ET数据。12名健康对照者（6名年轻人和6名老年人）以及7名诊断为单次缺血性中风的患者（4名没有USN，3名确诊有USN）完成了可用性调查。SUS结果显示该系统对于健康对照者和没有USN的中风患者具有良好的可接受性。ET结果显示，与健康对照者和没有USN的中风患者相比，有USN的患者表现较差，尤其是在探索左视野时。结果表明，所提出的iVR-ET生物反馈方案对于有USN的患者是一种安全且耐受性良好的技术。实时反馈可以引发一种性能反应，支持将其作为一种治疗方法进行研究。
