Wu Chung-Chun, Chen Mei-Shu, Chen Jen-Yang
Translational Cell Therapy Center, Department of Medical Research, China Medical University Hospital, Taichung City 404447, Taiwan.
National Institute of Cancer Research, National Health Research Institutes, Zhunan 350401, Taiwan.
Biomedicines. 2024 Feb 21;12(3):486. doi: 10.3390/biomedicines12030486.
Nasopharyngeal carcinoma (NPC) is a malignancy prevailing in Taiwan, Hong Kong, Southern China, Southeast Asia, and North Africa. Although early-stage NPC responds well to the primary treatment of radio-chemotherapy, the mortality rate of advanced NPC remains high. Therefore, developing new therapies for nasopharyngeal carcinoma is an urgent task. Emodin is an anthraquinone derivative mainly found in . Emodin has been found to possess many anti-cancer functions against various types of cancers, but they are less discussed in the treatment of NPC. This review organized the different studies about the anti-NPC activity of emodin and discussed the potential and challenges of emodin treatment in NPC therapy.
鼻咽癌(NPC)是一种在台湾、香港、中国南方、东南亚和北非地区盛行的恶性肿瘤。尽管早期鼻咽癌对放化疗的初始治疗反应良好,但晚期鼻咽癌的死亡率仍然很高。因此,开发鼻咽癌的新疗法是一项紧迫的任务。大黄素是一种主要存在于……的蒽醌衍生物。已发现大黄素对多种类型的癌症具有许多抗癌功能,但在鼻咽癌治疗方面的讨论较少。本综述整理了关于大黄素抗鼻咽癌活性的不同研究,并讨论了大黄素在鼻咽癌治疗中的潜力和挑战。