Department of Surgical Oncology, Masaryk Memorial Cancer Institute, 602 00 Brno, Czech Republic.
Department of Surgery, Silesian Hospital in Opava, 746 01 Opava, Czech Republic.
Medicina (Kaunas). 2024 Feb 26;60(3):399. doi: 10.3390/medicina60030399.
: Symptomatic calcifications of the breast or skin after breast cancer surgery and adjuvant radiotherapy are a rare entity, with only a few case reports published worldwide, reducing the patient's quality of life, whilst asymptomatic calcifications are a common finding on imaging methods. : Herein, we present a rare case report of calcifications after mastectomy and post-mastectomy radiation therapy causing chronic inflammation with ulceration and fistula formation, with a two-step surgical approach consisting of excision with linear suture and excision with the reconstruction using a thoraco-epigastric flap. : To our knowledge, this is the first publication proving the feasibility of this therapy in patients with symptomatic dystrophic calcifications of the skin or the breast. Moreover, the article provides an up-to-date review of published studies about symptomatic calcifications after breast cancer surgery and radiotherapy with a focus on the time of the clinical manifestation from the radiotherapy and the used radiotherapy scheme.
: 乳腺癌手术后和辅助放疗后出现的乳房或皮肤有症状的钙化是一种罕见的实体，全世界仅发表了少数几例病例报告，降低了患者的生活质量，而无症状的钙化是影像学方法上的常见发现。: 在此，我们报告了一例罕见病例，即乳房切除术和乳房切除术放疗后钙化导致慢性炎症伴溃疡和瘘形成，采用两步手术方法，包括线性缝合切除和使用胸-上腹皮瓣重建切除。: 据我们所知，这是第一篇证明这种疗法对有症状的皮肤或乳房营养不良性钙化患者可行性的出版物。此外，本文还对发表的关于乳腺癌手术后和放疗后有症状钙化的研究进行了最新回顾，重点关注从放疗开始到临床表现的时间以及使用的放疗方案。
