特应性皮炎病程中瘙痒症生物治疗的疗效与效果
The Efficacy and Effectiveness of the Biological Treatment of Pruritus in the Course of Atopic Dermatitis.
作者信息
Hołdrowicz Agnieszka Marta, Woźniacka Anna
机构信息
Department of Dermatology and Venereology, Medical University of Lodz, 90-647 Lodz, Poland.
出版信息
J Clin Med. 2024 Mar 18;13(6):1754. doi: 10.3390/jcm13061754.
Atopic dermatitis is a heterogenous inflammatory disease with high variety in terms of clinical symptoms and etiopathogenesis, occurring both in pediatric and adult populations. The clinical manifestation of atopic dermatitis varies depending on the age of patients, but all age groups share certain common features, such as a chronic and recurrent course of disease, pruritus, and a co-occurrence of atopic diseases in personal or family medical history. Treating pruritus is a high priority due to its incidence rate in atopic dermatitis and substantial impact on quality of life. In recent years, treatments with biological drugs have increased the range of therapeutic possibilities in atopic dermatitis. The aim of the study is to present the safety profile, efficacy, and effectiveness of various biological treatment methods for the therapy of pruritus in the course of atopic dermatitis.
特应性皮炎是一种异质性炎症性疾病，在临床症状和病因发病机制方面具有高度多样性，在儿童和成人中均可发生。特应性皮炎的临床表现因患者年龄而异，但所有年龄组都有某些共同特征，如疾病的慢性复发性病程、瘙痒，以及个人或家族病史中有特应性疾病的共同出现。由于瘙痒在特应性皮炎中的发生率及其对生活质量的重大影响，治疗瘙痒是当务之急。近年来，生物药物治疗增加了特应性皮炎治疗的可能性范围。本研究的目的是介绍各种生物治疗方法治疗特应性皮炎过程中瘙痒的安全性、疗效和有效性。
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