Department of Medicine and Surgery, University of Perugia, Unit of Internal Medicine, Terni University Hospital, Piazzale Tristano Di Joannuccio, 1, 05100 Terni, Italy.
Section of Endocrinology and Metabolism, Department of Medicine and Surgery, University of Perugia Medical School, 06132 Perugia, Italy.
Nutrients. 2024 Mar 21;16(6):907. doi: 10.3390/nu16060907.
Type 1 diabetes mellitus (T1DM) represents a complex clinical challenge for health systems. The autoimmune destruction of pancreatic beta cells leads to a complete lack of insulin production, exposing people to a lifelong risk of acute (DKA, coma) and chronic complications (macro and microvascular). Physical activity (PA) has widely demonstrated its efficacy in helping diabetes treatment. Nutritional management of people living with T1DM is particularly difficult. Balancing macronutrients, their effects on glycemic control, and insulin treatment represents a complex clinical challenge for the diabetologist. The effects of PA on glycemic control are largely unpredictable depending on many individual factors, such as intensity, nutrient co-ingestion, and many others. Due to this clinical complexity, we have reviewed the actual scientific literature in depth to help diabetologists, sport medicine doctors, nutritionists, and all the health figures involved in diabetes care to ameliorate both glycemic control and the nutritional status of T1DM people engaging in PA. Two electronic databases (PubMed and Scopus) were searched from their inception to January 2024. The main recommendations for carbohydrate and protein ingestion before, during, and immediately after PA are explained. Glycemic management during such activity is widely reviewed. Micronutrient needs and nutritional supplement effects are also highlighted in this paper.
1 型糖尿病(T1DM)对医疗系统构成了复杂的临床挑战。胰岛β细胞的自身免疫性破坏导致胰岛素完全缺乏,使患者终生面临急性(DKA、昏迷)和慢性并发症(大血管和微血管)的风险。身体活动(PA)已广泛证明其在帮助糖尿病治疗方面的有效性。1 型糖尿病患者的营养管理特别困难。平衡宏量营养素、它们对血糖控制的影响以及胰岛素治疗,这对糖尿病医生来说是一个复杂的临床挑战。PA 对血糖控制的影响在很大程度上是不可预测的,这取决于许多个体因素,如强度、营养物质共同摄入等。鉴于这种临床复杂性,我们深入回顾了实际的科学文献,以帮助糖尿病医生、运动医学医生、营养师以及参与糖尿病护理的所有卫生专业人员改善 PA 患者的血糖控制和营养状况。从数据库建立到 2024 年 1 月,我们在两个电子数据库(PubMed 和 Scopus)中进行了检索。解释了在 PA 之前、期间和之后摄入碳水化合物和蛋白质的主要建议。本文还广泛回顾了在这种活动期间的血糖管理。本文还强调了微量营养素需求和营养补充剂的作用。