Jansen Maarten, Spasenoska Dijana, Nadjib Mardiati, Ararso Desalegn, Hutubessy Raymond, Kahn Anna-Lea, Lambach Philipp
Immunization, Vaccines and Biologicals Department, World Health Organization, 1202 Geneva, Switzerland.
Department of Social Policy, London School of Economics and Political Science, London WC2A 2AE, UK.
Vaccines (Basel). 2024 Mar 20;12(3):337. doi: 10.3390/vaccines12030337.
To ensure that limited domestic resources are invested in the most effective interventions, immunization programs in low- and middle-income countries (LMICs) must prioritize a growing number of new vaccines while considering opportunities to optimize the vaccine portfolio, as well as other components of the health system. There is a strong impetus for immunization decision-making to engage and coordinate various stakeholders across the health system in prioritization. To address this, national immunization program decision-makers in LMICs collaborated with WHO to structure deliberation among stakeholders and document an evidence-based, context-specific, and transparent process for prioritization or selection among multiple vaccination products, services, or strategies. The output of this effort is the Country-led Assessment for Prioritization on Immunization (CAPACITI) decision-support tool, which supports using multiple criteria and stakeholder perspectives to evaluate trade-offs affecting health interventions, taking into account variable data quality. Here, we describe the user feedback from Indonesia and Ethiopia, two initial countries that piloted the CAPACITI decision-support tool, highlighting enabling and constraining factors. Potential immunization program benefits and lessons learned are also summarized for consideration in other settings.
为确保有限的国内资源投资于最有效的干预措施,低收入和中等收入国家(LMICs)的免疫规划必须在考虑优化疫苗组合以及卫生系统其他组成部分的机会的同时,优先考虑越来越多的新疫苗。免疫决策有强大的动力促使卫生系统中的各利益相关方参与并协调疫苗优先排序工作。为解决这一问题,低收入和中等收入国家的国家免疫规划决策者与世卫组织合作,组织利益相关方进行审议,并记录一个基于证据、因地制宜且透明的多重疫苗产品、服务或策略的优先排序或选择过程。这项工作的成果是国家主导的免疫优先排序评估(CAPACITI)决策支持工具,该工具支持使用多种标准和利益相关方的观点来评估影响卫生干预措施的权衡取舍,同时考虑到数据质量的差异。在此,我们描述了印度尼西亚和埃塞俄比亚这两个率先试点CAPACITI决策支持工具的国家的用户反馈,突出了促成因素和制约因素。还总结了潜在的免疫规划益处和经验教训,以供其他环境参考。