Omo-Ogboi Allen C, Ederhion Joyce, Ur Rehman Asad, Ogunleye Olanrewaju, Thomas-Ogunniyi Jaiyeola
Department of Pathology and Laboratory Medicine, The University of Texas Health Science Center, Houston, USA.
Department of Neuroscience and Immunology, University of Roehampton, London, GBR.
Cureus. 2024 Feb 26;16(2):e54942. doi: 10.7759/cureus.54942. eCollection 2024 Feb.
Pulmonary alveolar microlithiasis (PAM) is an autosomal recessive disease of the lung, characterized by diffuse deposits of intra-alveolar calcium phosphate microliths. It usually affects both sexes, presenting mostly in the second and third decades. The clinical course is highly variable, ranging from being asymptomatic to respiratory failure. PAM is usually diagnosed after careful clinical, radiological, and pathological evaluation, usually when patients present for other medical purposes. Here, a case of PAM in a middle-aged man presenting with acute-on-chronic hypoxemic respiratory failure is reported, with a review of the literature.
肺泡微石症（PAM）是一种常染色体隐性遗传性肺部疾病，其特征为肺泡内磷酸钙微结石的弥漫性沉积。该病通常累及两性，多在第二和第三个十年发病。临床病程差异很大，从无症状到呼吸衰竭不等。PAM通常在经过仔细的临床、影像学和病理学评估后确诊，通常是在患者因其他医疗目的就诊时。本文报告一例中年男性PAM患者，表现为慢性低氧性呼吸衰竭急性发作，并对相关文献进行了综述。
