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肝弥漫性大B细胞淋巴瘤:一例报告及原发性肝脏肿瘤文献综述

Hepatic Diffuse Large B-cell Lymphoma: A Case Report and Review of Literature of Primary Liver Tumors.

作者信息

Pérez-Turrent Manuel A, Hernández-Solís Jesús I, Sánchez Antonio Estrella Elizabeth, Trinidad-Esparza Cristina V, Herrera-Esquivel José J

机构信息

Gastrointestinal Endoscopy, Hospital General "Dr. Manuel Gea González", Mexico City, MEX.

Pathological Anatomy, Instituto Nacional de Cancerología, Mexico City, MEX.

出版信息

Cureus. 2024 Feb 26;16(2):e54947. doi: 10.7759/cureus.54947. eCollection 2024 Feb.

Abstract

Liver tumors rank as the fourth most common cause of cancer. This case report highlights a 45-year-old female patient who presented persistent abdominal pain and no other symptoms. Initially, she was approached with a probable hepatitis of unknown origin, but her condition worsened rapidly. An endoscopic ultrasound was used to characterize the lesion, and a fine needle biopsy of the lesion was performed which revealed a diffuse large B-cell lymphoma that is CD20+ and Ki67+. Hepatic diffuse large B-cell lymphoma, as diagnosed in the patient, is a rare type of lymphoma that arises in the liver. The treatment usually involves chemotherapy, immunotherapy, and radiation therapy. However, the prognosis depends on the stage of the disease and the patient's overall health. This case reinforces the importance of considering hepatic diffuse large B-cell lymphoma in differential diagnosis for primary liver neoplasia.

摘要

肝脏肿瘤是癌症的第四大常见病因。本病例报告着重介绍了一名45岁女性患者,该患者持续腹痛,无其他症状。起初,她被诊断为可能患有不明原因的肝炎,但病情迅速恶化。通过内镜超声对病变进行特征描述,并对病变进行细针穿刺活检,结果显示为弥漫性大B细胞淋巴瘤,CD20阳性且Ki67阳性。如该患者所诊断的肝弥漫性大B细胞淋巴瘤是一种罕见的起源于肝脏的淋巴瘤类型。治疗通常包括化疗、免疫疗法和放射疗法。然而,预后取决于疾病的分期和患者的整体健康状况。本病例强化了在原发性肝脏肿瘤的鉴别诊断中考虑肝弥漫性大B细胞淋巴瘤的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d922/10966637/e55785fdffc0/cureus-0016-00000054947-i01.jpg

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