Liaw Victor, Park Jason, Barth Bradley, Santolaya Jacobo
University of Texas Southwestern Medical School Dallas Texas USA.
Department of Pathology University of Texas Southwestern Medical Center Dallas Texas USA.
JPGN Rep. 2023 Dec 20;5(1):79-82. doi: 10.1002/jpr3.12020. eCollection 2024 Feb.
Filiform polyposis (FP) is a morphologic variant of pseudopolyposis associated with inflammatory conditions of the gastrointestinal tract, namely, inflammatory bowel disease. Pediatric cases are uncommon in the literature. Here, we present a pediatric patient with FP arising from ulcerative colitis (UC). He initially presented at 7 years of age for an acute UC flare and was found to have classical pseudopolyposis. A follow-up colonoscopy at age 9 showed the evolution of classical pseudopolyposis to FP. The patient clinically improved with sulfasalazine monotherapy and remained in remission based on consistent pediatric ulcerative colitis activity index scores of zero and normal-range inflammatory markers. Repeat surveillance colonoscopy at age 14 showed persistent and diffuse FP in the background of healthy colonic mucosa. This case documents the development of FP from classical pseudopolyps in the setting of an asymptomatic patient in clinical remission.
丝状息肉病（FP）是一种与胃肠道炎症性疾病（即炎症性肠病）相关的假息肉病形态学变体。儿科病例在文献中并不常见。在此，我们报告一名因溃疡性结肠炎（UC）引发丝状息肉病的儿科患者。他最初在7岁时因急性UC发作就诊，被发现患有典型的假息肉病。9岁时的随访结肠镜检查显示，典型假息肉病已演变为丝状息肉病。该患者使用柳氮磺胺吡啶单药治疗后临床症状改善，基于一致的儿科溃疡性结肠炎活动指数评分为零且炎症标志物在正常范围内，病情保持缓解。14岁时的重复监测结肠镜检查显示，在健康结肠黏膜背景下存在持续性弥漫性丝状息肉病。该病例记录了在临床缓解的无症状患者中，丝状息肉病从典型假息肉发展而来的过程。
