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一名婴儿因过量饮用杏仁奶替代配方奶粉而继发症状性高钙血症。

Symptomatic hypercalcemia in an infant secondary to excessive consumption of almond milk as a formula alternative.

作者信息

Gulledge Whitney C, Gerald Brittany M, Sumpter Kathryn M, Rogers Nathaniel G

机构信息

Department of Pediatrics University of Tennessee Health Science Center Memphis Tennessee USA.

Department of Pediatrics Le Bonheur Children's Hospital Memphis Tennessee USA.

出版信息

JPGN Rep. 2023 Dec 28;5(1):90-92. doi: 10.1002/jpr3.12028. eCollection 2024 Feb.

DOI:10.1002/jpr3.12028
PMID:38545269
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10964333/
Abstract

A 4-month-old previously healthy female presented with persistent nonbloody, nonbilious emesis, decreased urine output, weight loss, fussiness, and lethargy. Serum levels of calcium were increased at 14.1 mg/dL, serum phosphate decreased at 1.6 mg/dL, and serum parathyroid hormone decreased at <4 pg/mL. The patient had been consuming unsweetened almond milk due to inability to find infant formula during a national infant formula shortage. Milk alternatives including almond milk are calorie-poor, low fat, low protein, and too high in free water and calcium to safely be the primary nutrition source for infants.

摘要

一名4个月大、此前健康的女婴出现持续性非血性、非胆汁性呕吐、尿量减少、体重减轻、烦躁和嗜睡症状。血清钙水平升高至14.1毫克/分升,血清磷降低至1.6毫克/分升,血清甲状旁腺激素降低至<4皮克/毫升。在全国婴儿配方奶粉短缺期间,由于找不到婴儿配方奶粉,该患者一直在饮用无糖杏仁奶。包括杏仁奶在内的替代奶热量低、脂肪低、蛋白质低,且游离水和钙含量过高,无法安全地作为婴儿的主要营养来源。

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Symptomatic hypercalcemia in an infant secondary to excessive consumption of almond milk as a formula alternative.一名婴儿因过量饮用杏仁奶替代配方奶粉而继发症状性高钙血症。
JPGN Rep. 2023 Dec 28;5(1):90-92. doi: 10.1002/jpr3.12028. eCollection 2024 Feb.
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Ochsner J. 2025 Spring;25(1):64-66. doi: 10.31486/toj.24.0067.

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Hypophosphatemia: A Practical Guide to Evaluation and Management.低磷血症:评估与管理实用指南。
Endocr Pract. 2022 Oct;28(10):1091-1099. doi: 10.1016/j.eprac.2022.07.005. Epub 2022 Aug 6.
2
Plant-Based Milk Alternatives and Risk Factors for Kidney Stones and Chronic Kidney Disease.植物基奶替代品与肾结石和慢性肾脏病风险因素的关系。
J Ren Nutr. 2022 May;32(3):363-365. doi: 10.1053/j.jrn.2021.03.011. Epub 2021 May 25.
3
A Nutritional Comparison of Cow's Milk and Alternative Milk Products.牛奶奶制品与其他代乳品的营养成分比较。
Acad Pediatr. 2021 Aug;21(6):1067-1069. doi: 10.1016/j.acap.2020.12.007. Epub 2020 Dec 26.
4
A Case of Hyponatremia-induced Seizures in an Infant Secondary to Water Intoxication from the Use of Almond Milk.一例因饮用杏仁奶导致水中毒继发低钠血症性惊厥的婴儿病例。
Cureus. 2019 Oct 13;11(10):e5899. doi: 10.7759/cureus.5899.
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Cow's Milk Substitutes for Children: Nutritional Aspects of Milk from Different Mammalian Species, Special Formula and Plant-Based Beverages.婴幼儿代乳品:不同哺乳动物来源奶、特殊配方奶及植物基饮品的营养问题。
Nutrients. 2019 Jul 27;11(8):1739. doi: 10.3390/nu11081739.
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The nutritional limitations of plant-based beverages in infancy and childhood.植物基饮料在婴幼儿期和儿童期的营养限制
Nutr Hosp. 2017 Oct 24;34(5):1205-1214. doi: 10.20960/nh.931.
7
Improper Use of a Plant-Based Vitamin C-Deficient Beverage Causes Scurvy in an Infant.不当饮用植物性维生素C缺乏饮料导致婴儿患坏血病。
Pediatrics. 2016 Feb;137(2):e20152781. doi: 10.1542/peds.2015-2781. Epub 2016 Jan 18.
8
The diagnosis and management of hypercalcaemia.高钙血症的诊断与管理
BMJ. 2015 Jun 2;350:h2723. doi: 10.1136/bmj.h2723.
9
[Severe nutritional deficiencies in young infants with inappropriate plant milk consumption].[不适当饮用植物奶的幼儿严重营养缺乏症]
Arch Pediatr. 2014 May;21(5):483-8. doi: 10.1016/j.arcped.2014.02.027. Epub 2014 Apr 13.
10
Hypercalcemia in children and adolescents.儿童和青少年高钙血症。
Curr Opin Pediatr. 2010 Aug;22(4):508-15. doi: 10.1097/MOP.0b013e32833b7c23.