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合并变应性支气管肺真菌病和嗜酸性肉芽肿性多血管炎:一例报告及文献复习

Combined allergic bronchopulmonary mycosis and eosinophilic granulomatosis with polyangiitis: A case report and literature review.

作者信息

Cui Ning, Wang Jingluan, Shao Yanmei, Zhao Jingming, Cheng Zhaozhong

机构信息

Department of Respiratory and Critical Care Medicine, The Affiliated Hospital of Qingdao University, Qingdao, 266000, Shandong, China.

出版信息

Respir Med Case Rep. 2024 Mar 19;48:102012. doi: 10.1016/j.rmcr.2024.102012. eCollection 2024.

Abstract

A 27-year-old female visited our hospital with a history of asthma, peripheral blood eosinophilia, increased total IgE, Aspergillus fumigatus specific IgE, reversible mild bronchiectasis, sinusitis, bronchial mucus plugs and cultivation of Aspergillus from BALF. Glucocorticoids therapy is effective. These results met the diagnostic criteria for both allergic bronchopulmonary aspergillosis (ABPM) and eosinophilic granulomatosis with polyangiitis (EGPA). Special attention should be paid to the possibility of both diseases coexisting in the disease process.

摘要

一名27岁女性因哮喘病史、外周血嗜酸性粒细胞增多、总IgE升高、烟曲霉特异性IgE、可逆性轻度支气管扩张、鼻窦炎、支气管黏液栓以及支气管肺泡灌洗(BALF)培养出曲霉菌而前来我院就诊。糖皮质激素治疗有效。这些结果符合变应性支气管肺曲霉菌病(ABPM)和嗜酸性肉芽肿性多血管炎(EGPA)的诊断标准。在疾病过程中应特别注意这两种疾病共存的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fe7/10966086/37ed2614dba2/gr1.jpg

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