Kumar Ravi, Meher Rohan Kumar, Karmakar Himadri, Panda Tarun K
Department of Chemistry, Indian Institute of Technology Hyderabad, Kandi, Sangareddy 502284, Telangana, India.
Org Biomol Chem. 2024 Apr 17;22(15):3053-3058. doi: 10.1039/d4ob00161c.
We report a competent and selective hydrosilylation of nitriles and tertiary amides catalyzed by the readily available zinc bis(hexamethyldisilazide) under solvent-free and mild conditions, making it a sustainable and desirable alternative to existing methods. Both protocols afforded high conversion, superior selectivity, and a broad substrate scope, from electron-withdrawing to electron-donating and heterocyclic substitutions.
我们报道了一种在无溶剂温和条件下，由易于获得的双（六甲基二硅氮基）锌催化的腈和叔酰胺的高效且选择性的硅氢化反应，使其成为现有方法的一种可持续且理想的替代方法。两种方案都实现了高转化率、优异的选择性以及广泛的底物范围，涵盖了从吸电子到给电子以及杂环取代的底物。
