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病例报告:以无热惊厥形式就诊于急诊科的小儿甲状腺风暴。

Case Report: Pediatric Thyroid Storm Presenting to the Emergency Department with Afebrile Seizure.

作者信息

Klein Daniel J, Rose Emily

机构信息

Los Angeles General Medical Center, Keck School of Medicine of the University of Southern California, Department of Emergency Medicine, Los Angeles, California.

出版信息

Clin Pract Cases Emerg Med. 2024 Feb;8(1):5-8. doi: 10.5811/cpcem.1359.

DOI:10.5811/cpcem.1359
PMID:38546301
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10966502/
Abstract

INTRODUCTION

Seizures are a common presenting complaint and account for approximately 1% of total emergency department (ED) visits. Seizures are especially common in children less than five years old as they have a lower seizure threshold as compared to adults. One potentially dangerous etiology that is far less common, especially in children, is thyroid storm, the extreme manifestation of hyperthyroidism.

CASE REPORT

We describe the case of a 3-year-old girl who presented to the ED with an afebrile seizure but was found to be in thyroid storm. This case should serve as a reminder for emergency physicians to consider thyroid disease when evaluating patients presenting with seizures.

CONCLUSION

Although most pediatric seizures are self-limited and frequently benign, it is imperative that the emergency physician evaluate for and rule out any potentially associated dangerous conditions such as thyroid storm.

摘要

引言

癫痫发作是常见的就诊主诉,约占急诊科就诊总数的1%。癫痫发作在5岁以下儿童中尤为常见,因为与成人相比,他们的癫痫发作阈值较低。一种潜在危险的病因,尤其是在儿童中极为罕见的,是甲状腺风暴,即甲状腺功能亢进的极端表现。

病例报告

我们描述了一名3岁女孩的病例,她因无热惊厥到急诊科就诊,但被发现处于甲状腺风暴状态。该病例应提醒急诊医生,在评估癫痫发作的患者时要考虑甲状腺疾病。

结论

虽然大多数小儿癫痫发作是自限性的,且通常是良性的,但急诊医生必须评估并排除任何潜在相关的危险情况,如甲状腺风暴。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7963/10966502/c8ddf0daef7e/cpcem-8-5-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7963/10966502/ac3190ce3d47/cpcem-8-5-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7963/10966502/c8ddf0daef7e/cpcem-8-5-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7963/10966502/ac3190ce3d47/cpcem-8-5-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7963/10966502/c8ddf0daef7e/cpcem-8-5-g002.jpg

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本文引用的文献

1
Hyperthyroidism in adolescents.青少年甲状腺功能亢进症
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Long-Term Antithyroid Drug Treatment of Graves' Disease in Children and Adolescents: A 20-Year Single-Center Experience.儿童和青少年 Graves 病的长期抗甲状腺药物治疗:20 年单中心经验。
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Thyroid Storm in a Toddler Presenting as a Febrile Seizure.幼儿甲状腺危象表现为热性惊厥。
Pediatrics. 2020 Feb;145(2). doi: 10.1542/peds.2019-1920.
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Emergency department management of seizures in pediatric patients.儿科患者癫痫发作的急诊科管理
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Clinical features and hospital outcomes in thyroid storm: a retrospective cohort study.甲状腺危象的临床特征与住院结局:一项回顾性队列研究
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Febrile seizures.热性惊厥
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Thyroid storm: an updated review.甲状腺危象:最新综述
J Intensive Care Med. 2015 Mar;30(3):131-40. doi: 10.1177/0885066613498053. Epub 2013 Aug 5.
10
Diagnostic criteria, clinical features, and incidence of thyroid storm based on nationwide surveys.基于全国性调查的甲状腺危象的诊断标准、临床特征和发生率。
Thyroid. 2012 Jul;22(7):661-79. doi: 10.1089/thy.2011.0334. Epub 2012 Jun 12.