Guin Amit Kumar, Chakraborty Subhajit, Khanra Subhankar, Chakraborty Santana, Paul Nanda D
Department of Chemistry, Indian Institute of Engineering Science and Technology, Shibpur, Botanic Garden, Howrah 711103, India.
Org Lett. 2024 Apr 5;26(13):2540-2545. doi: 10.1021/acs.orglett.4c00455. Epub 2024 Mar 28.
An oxygen-dependent ligand-controlled chemoselective synthesis of vinyl nitriles and -olefins by coupling a variety of alcohols and benzyl cyanides, catalyzed by a well-characterized, air-stable, easy-to-prepare Fe(II) catalyst () bearing a redox-active arylazo pincer () is reported. The azo-moiety of the ligand backbone acts as an electron and hydrogen reservoir, enabling catalyst to efficiently produce a broad spectrum of vinyl nitriles and -olefins in moderate to good yields selectively under an oxygen and argon atmosphere, respectively.
据报道，通过一种具有明确结构、空气稳定且易于制备的带有氧化还原活性芳基偶氮钳形配体（）的铁（II）催化剂（），将多种醇类与苄基氰化物进行偶联，可实现氧依赖型配体控制的乙烯基腈和烯烃的化学选择性合成。配体骨架的偶氮部分充当电子和氢的储存库，使催化剂能够分别在氧气和氩气气氛下，以中等至良好的产率选择性地高效制备多种乙烯基腈和烯烃。
