Pritzker School of Medicine, The University of Chicago, Chicago, IL, USA.
Pritzker School of Medicine, The University of Chicago, Chicago, IL, USA.
World Neurosurg. 2024 Jun;186:e326-e334. doi: 10.1016/j.wneu.2024.03.130. Epub 2024 Mar 26.
Idiopathic intracranial hypertension (IIH) is a cerebrospinal fluid (CSF) disorder defect that is frequently treated with CSF shunts. Shunts utilizing the cisterna magna as a proximal reservoir have been described in literature; however, long-term outcomes are unknown. The present study aims to describe the long-term effectiveness, revision rates, and clinical outcomes of this shunt in 14 patients with IIH and slit ventricles.
A single-center retrospective review of 14 IIH patients treated by cisterna magna shunts was performed. Shunt histories, including revision rate and time until first shunt failure for ventricular, lumbar, and cisterna magna shunts were recorded. "Revision rate" was calculated as the total number of shunt revisions over years of total shunt placement. The average follow-up time was 12.08 years.
The mean age at first cisterna magna shunt placement was 18.1 years (6.6-43.3 years) and all patients had radiological evidence of slit ventricles. Cisterna magna shunts improved or resolved clinical symptoms for all 14 patients and had a lower rate of revisions (0.42 revision/year) compared to ventricular (0.72 revision/year) and lumbar (1.30 revision/year) shunts. Of the 11 patients still requiring CSF diversion at the end of the study, eight had functioning shunts that utilized the cisterna magna.
The cisterna magna shunt may be a suitable option for patients with IIH and slit ventricles. Further study is needed to understand the clinical utility of this shunt for the population in which it is indicated.
特发性颅内高压(IIH)是一种脑脊液(CSF)紊乱缺陷,常采用 CSF 分流术进行治疗。文献中已有描述将小脑延髓池作为近端储液器的分流术;然而,其长期结果尚不清楚。本研究旨在描述 14 例 IIH 伴狭缝脑室患者采用这种分流术的长期效果、翻修率和临床结果。
对 14 例 IIH 患者采用小脑延髓池分流术进行了单中心回顾性研究。记录了分流术病史,包括脑室、腰椎和小脑延髓池分流术的翻修率和首次分流失败的时间。“翻修率”的计算方法为分流术总放置年限内的总分流术翻修次数。平均随访时间为 12.08 年。
首次小脑延髓池分流术的平均年龄为 18.1 岁(6.6-43.3 岁),所有患者均有狭缝脑室的影像学证据。小脑延髓池分流术改善或解决了所有 14 例患者的临床症状,且其翻修率(0.42 次/年)低于脑室分流术(0.72 次/年)和腰椎分流术(1.30 次/年)。在研究结束时仍需要 CSF 分流的 11 例患者中,8 例具有功能良好的小脑延髓池分流术。
小脑延髓池分流术可能是 IIH 伴狭缝脑室患者的一种合适选择。需要进一步研究以了解该分流术在其适应证人群中的临床应用价值。