Section of Neonatal Imaging, Division of Body Imaging, Department of Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.
Department of Radiology, Perelman School of Medicine, University of Pennsylvania, 3401 Civic Center Boulevard, Philadelphia, PA, 19104, USA.
J Ultrasound. 2024 Dec;27(4):911-915. doi: 10.1007/s40477-023-00867-4. Epub 2024 Mar 28.
Bacterial meningitis is a severe and life-threatening disease that rapidly progresses in neonates and infants; prompt diagnosis and appropriate treatment are lifesaving. Magnetic resonance imaging remains the primary imaging technique for diagnosing meningitis; however, due to its limited availability and cost, ultrasound is often used for initial screening. Microvascular imaging ultrasound (MVI) is an emerging technique that offers insight into the brain microvasculature beyond conventional ultrasound. Here we present three patients with confirmed bacterial meningitis and associated cerebral microvascular findings on brain MVI to instigate further validation of cerebral microvascular imaging markers of bacterial meningitis for early detection and intervention.
细菌性脑膜炎是一种严重且危及生命的疾病,在新生儿和婴儿中迅速进展;及时诊断和适当的治疗是挽救生命的关键。磁共振成像仍然是诊断脑膜炎的主要影像学技术;然而,由于其可用性和成本有限,超声通常用于初步筛查。微血管成像超声(MVI)是一种新兴技术,它提供了对大脑微血管的深入了解,超越了传统的超声。在这里,我们介绍了 3 名经证实患有细菌性脑膜炎的患者,并在脑 MVI 上发现了相关的脑微血管病变,以进一步验证细菌性脑膜炎的脑微血管成像标志物,用于早期发现和干预。