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[经鼻内镜下斜坡脑膜瘤切除术]

[Endoscopic transnasal resection of clival meningiomas].

作者信息

Shkarubo A N, Chernov I V, Veselkov A A, Andreev D N, Yakupova Z F, Kalinin P P

机构信息

Burdenko Neurosurgical Center, Moscow, Russia.

Peoples' Friendship University of Russia, Moscow, Russia.

出版信息

Zh Vopr Neirokhir Im N N Burdenko. 2024;88(2):105-111. doi: 10.17116/neiro202488021105.

Abstract

BACKGROUND

Surgical treatment of ventral and ventrolateral meningiomas of posterior cranial fossa is difficult in modern neurosurgery. This is due to peculiarities of approach to these areas and concentration of critical structures (cranial nerves and great vessels). Currently, endoscopic transnasal approach to these meningiomas allows partial, and in some cases, total resection. However, this technique is not widespread.

OBJECTIVE

To analyze the world literature data on postoperative outcomes in patients with clival and petroclival meningiomas after endoscopic transnasal resection.

MATERIAL AND METHODS

We analyzed 22 articles representing treatment of 61 patients with clival and petroclival meningiomas.

RESULTS

Total or near-total resection was achieved in 22.9% of cases, subtotal resection - 40.9%, partial resection - 26.2% (data were not provided in other cases). Even partial and subtotal resection leads to significant regression of symptoms.

CONCLUSION

Endoscopic transnasal surgery is a full-fledged alternative to transcranial approaches in surgical treatment of clival meningiomas. It is also an additional option for patients with petroclival meningiomas after ineffective transcranial approaches. Transnasal tumor shrinkage and devascularization lead to brainstem decompression, regression of hydrocephalus and baseline clinical symptoms.

摘要

背景

在现代神经外科手术中,后颅窝腹侧和腹外侧脑膜瘤的手术治疗具有挑战性。这是由于这些区域的手术入路特点以及关键结构(颅神经和大血管)的集中分布。目前,内镜经鼻入路治疗这些脑膜瘤可实现部分切除,在某些情况下甚至可实现全切除。然而,这项技术尚未广泛应用。

目的

分析世界文献中关于内镜经鼻切除斜坡和岩斜脑膜瘤患者术后结局的数据。

材料与方法

我们分析了22篇关于61例斜坡和岩斜脑膜瘤治疗的文章。

结果

22.9%的病例实现了全切除或近全切除,次全切除占40.9%,部分切除占26.2%(其他病例未提供数据)。即使是部分切除和次全切除也能使症状显著缓解。

结论

内镜经鼻手术是斜坡脑膜瘤手术治疗中经颅入路的一种成熟替代方法。对于经颅入路无效的岩斜脑膜瘤患者,它也是一种额外的选择。经鼻肿瘤缩小和去血管化可导致脑干减压、脑积水缓解和基线临床症状改善。

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