Sternberg Annika, Bethge Matthias, Ober Jona, Weier Lisa, Benninghoven Dieter
Institut für Sozialmedizin und Epidemiologie, Universität zu Lübeck.
Mühlenbergklinik Holsteinische Schweiz, Malente.
Rehabilitation (Stuttg). 2024 Jun;63(3):180-188. doi: 10.1055/a-2192-3688. Epub 2024 Mar 29.
Suicidality is rarely assessed in patients treated in German rehabilitation centers, although individuals with physical and mental impairments have an increased risk for suicidality. The item 9 of the 9-item depression module of the Patient Health Questionnaire (PHQ-9) asks about the desire to be dead or to harm oneself and could be used as a possible screening for suicidality. The Columbia Suicide Severity Rating Scale (C-SSRS) is a standardized interview to assess suicidality. We assessed the prevalence of suicidality in orthopedic and cardiac rehabilitation using the C-SSRS and the PHQ-9, examined the diagnostic accuracy of the item 9 of the PHQ-9 and of the PHQ-9 total score for identifying suicidality and surveyed the acceptance of the suicidality assessment by the rehabilitants.
Study participants were screened with the PHQ-9 and subsequently interviewed using C-SSRS. Sensitivity and specificity of the item 9 of the PHQ-9 and the PHQ-9 total score were tested for the presence of suicidality assessed with the C-SSRS and in a sensitivity analysis for the presence of nonspecific active suicidal ideation (item 2 of the C-SSRS). We calculated the area under the curve (AUC) to predict the ability of the PHQ-9 to discriminate between individuals with and without acute suicidality. Screening and interview were evaluated by the rehabilitants.
Among 405 study participants, the prevalence of acute suicidality measured by the C-SSRS was 0.5%. 4% reported nonspecific active suicidal ideation on the C-SSRS. 10.4% reported suicidal ideation on item 9 of the PHQ-9. The sensitivity of item 9 and the PHQ-9 total score for identifying acute suicidality was only 50.0% (95% CI: 1.3% to 98.7%). However, item 9 was sensitive (81.3%, 95% CI: 54.4% to 96.0%) and specific (92.5%, 95% CI: 89.5% to 95.0%) for identifying nonspecific active suicidal ideation. Estimators for sensitivity were highly uncertain because of the low prevalence of acute suicidality. Addressing suicidality was rated as useful and helpful by study participants.
If the response to item 9 is positive, the immediate risk of suicide is low. However, PHQ-9 is suitable for identifying patients with non-specific suicidal thoughts. A conspicuous score on the item 9 of the PHQ-9 should be further clarified by a psychotherapist.
尽管身心有障碍的个体自杀风险增加,但德国康复中心接受治疗的患者很少接受自杀倾向评估。患者健康问卷(PHQ - 9)的9项抑郁模块中的第9项询问了想死或伤害自己的愿望,可作为自杀倾向的一种可能筛查工具。哥伦比亚自杀严重程度评定量表(C - SSRS)是一种评估自杀倾向的标准化访谈工具。我们使用C - SSRS和PHQ - 9评估了骨科和心脏康复患者中自杀倾向的患病率,检验了PHQ - 9第9项和PHQ - 9总分在识别自杀倾向方面的诊断准确性,并调查了康复患者对自杀倾向评估的接受度。
研究参与者先用PHQ - 9进行筛查,随后使用C - SSRS进行访谈。针对用C - SSRS评估的自杀倾向以及在非特异性主动自杀意念(C - SSRS第2项)存在情况的敏感性分析中,测试了PHQ - 9第9项和PHQ - 9总分的敏感性和特异性。我们计算了曲线下面积(AUC)以预测PHQ - 9区分有和无急性自杀倾向个体的能力。康复患者对筛查和访谈进行了评价。
在405名研究参与者中,用C - SSRS测量的急性自杀倾向患病率为0.5%。4%的人在C - SSRS上报告有非特异性主动自杀意念。10.4%的人在PHQ - 9第9项上报告有自杀意念。PHQ - 9第9项和PHQ - 9总分识别急性自杀倾向的敏感性仅为50.0%(95%置信区间:1.3%至98.7%)。然而,PHQ - 9第9项在识别非特异性主动自杀意念方面敏感(81.3%,95%置信区间:54.4%至96.0%)且特异(92.5%,95%置信区间:89.5%至95.0%)。由于急性自杀倾向患病率低,敏感性估计值极不确定。研究参与者认为处理自杀倾向是有用且有帮助的。
如果对第9项的回答为阳性,自杀的直接风险较低。然而,PHQ - 9适用于识别有非特异性自杀想法的患者。PHQ - 9第9项上显著的分数应由心理治疗师进一步澄清。