Galin M A, Obstbaum S A, Asano Y, Kraff M, El Maghraby A
Trans Ophthalmol Soc U K (1962). 1985;104 ( Pt 1):72-5.
We have compared long-term intraocular pressure control in patients with open angle glaucoma, cupping and atrophy of the optic nerve head and visual field loss as well as cataract after: trabeculectomy posterior to the scleral spur and cataract extraction without implantation in 108 patients. guarded posterior lip sclerectomy, cataract extraction and Mark VIII or Mark IX anterior chamber implantation in 28 patients. argon laser trabeculoplasty followed by lens extraction and implantation in 27 patients. Approximately 75 per cent of patients achieve intraocular pressures of 18 mm Hg or less without medication after (a), and approximately 40 per cent of patients achieve similar control without medication after (b). Approximately 25 per cent of these glaucoma patients have intraocular pressure levels of less than or equal to 18 mm Hg on topical medication three months after ALT, and none achieve this control without medication. Cataract surgery with anterior or posterior chamber implantation caused loss of topical control in four of the seven patients benefiting from ALT. These data imply that combined surgery with or without implantation produces better and more significant intraocular pressure control than the presently utilized techniques of ALT subsequently followed by lens extraction and implantation.
我们比较了108例患者在以下治疗后的长期眼压控制情况:这些患者患有开角型青光眼、视神经乳头杯状凹陷与萎缩、视野缺损以及白内障。其中,108例患者接受了巩膜突后方小梁切除术及白内障摘除且未植入人工晶体;28例患者接受了后唇巩膜切除术、白内障摘除及Mark VIII或Mark IX前房人工晶体植入;27例患者接受了氩激光小梁成形术,随后进行晶状体摘除及植入。在(a)组治疗后,约75%的患者无需药物治疗即可使眼压降至18 mmHg或更低;在(b)组治疗后,约40%的患者无需药物治疗即可实现类似的眼压控制。在接受氩激光小梁成形术(ALT)三个月后,约25%的青光眼患者使用局部药物治疗时眼压水平小于或等于18 mmHg,且无一例患者无需药物治疗就能达到这种控制效果。在七例受益于ALT的患者中,有四例在进行前房或后房人工晶体植入的白内障手术后,局部眼压控制失效。这些数据表明,无论是否植入人工晶体,联合手术在眼压控制方面比目前采用的先进行ALT随后进行晶状体摘除及植入的技术效果更好、更显著。