Department of Cardiology, The First Affiliated Hospital of Guangxi Medical University, No. 6, Shuangyong Road, Qingxiu District, Nanning, 530021, Guangxi Zhuang Autonomous Region, China.
Sci Rep. 2024 Mar 29;14(1):7515. doi: 10.1038/s41598-024-58197-2.
Few studies explored the association of different type of physical activity with all-cause mortality in hypertension (HBP) participants. A retrospective cohort analysis was performed using National Health and Nutrition Examination Survey (NHANES) data to explore association of moderate-intensity physical activity (MPA), vigorous-intensity physical activity (VPA), sedentary behavior with mortality in HBP individuals. Among 10,913 HBP participants followed for a median of 6.2 years, VPA was not associated with a reduction in all-cause mortality compared to participants without VPA in multivariate Cox survival analysis. MPA was linked to lower all-cause mortality at durations of 0-150 min/week (HR, 0.72; 95% CI 0.58-0.88), 150-300 min/week (HR, 0.71; 95% CI 0.52-0.96), and > 300 min/week (HR, 0.61; 95% CI 0.49-0.77) compared to no MPA. Sedentary behavior of 6-8 h/day (HR, 1.35; 95% CI 1.15-1.59) and > 8 h/day (HR, 1.55; 95% CI 1.34-1.79) were associated with increased mortality risk versus < 6 h/day. Further research is needed to explore whether VPA can improve outcomes for HBP individuals and to determine the optimal duration of VPA.MPA is linked to lower mortality risk, indicating its potential as the best physical activity intensity for HBP individuals.
很少有研究探讨不同类型的身体活动与高血压（HBP）患者全因死亡率之间的关系。本回顾性队列分析使用国家健康和营养检查调查（NHANES）数据，旨在探讨中度强度体力活动（MPA）、剧烈强度体力活动（VPA）和久坐行为与 HBP 个体死亡率之间的关联。在中位随访 6.2 年的 10913 名 HBP 参与者中，多变量 Cox 生存分析显示，与没有 VPA 的参与者相比，VPA 与全因死亡率降低无关。在 0-150 分钟/周（HR，0.72；95%CI 0.58-0.88）、150-300 分钟/周（HR，0.71；95%CI 0.52-0.96）和>300 分钟/周（HR，0.61；95%CI 0.49-0.77）的 MPA 与全因死亡率降低相关，与没有 MPA 的参与者相比。6-8 小时/天（HR，1.35；95%CI 1.15-1.59）和>8 小时/天（HR，1.55；95%CI 1.34-1.79）的久坐行为与死亡率增加相关，与<6 小时/天相比。需要进一步研究以探讨 VPA 是否可以改善 HBP 个体的预后，并确定 VPA 的最佳持续时间。MPA 与较低的死亡率风险相关，表明其作为 HBP 个体最佳体力活动强度的潜力。
