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HIV 感染者和酒精使用者跌倒预防的可行性试验

A Fall Prevention Feasibility Trial for People With HIV and Alcohol Use.

机构信息

Boston University, MA, USA.

American International College, Springfield, MA, USA.

出版信息

OTJR (Thorofare N J). 2025 Jan;45(1):85-94. doi: 10.1177/15394492241238956. Epub 2024 Mar 30.

Abstract

Alcohol contributes to higher fall risk in people living with HIV (PLWH), yet fall prevention trials for PWH with alcohol use are lacking. To assess the feasibility of conducting a randomized controlled trial of a 10-week online fall prevention intervention tailored for PLWH with alcohol use. The intervention consisted of weekly virtual group discussions, individual phone check-ins, and home exercises. Of those eligible, 53.5% (23/43) enrolled (12 to the intervention and 11 to control). Mean age was 58 years; 82.6% had a past 6-month fall; 65.2% had alcohol use disorder; and 95.7% completed postintervention assessments. The intervention was highly rated (Client Satisfaction Questionnaire-8 score = 30.4, = 1.6) with a wide range of group and individual phone session attendance. Preliminary analyses suggest the intervention may reduce the odds of falling and alcohol use frequency. Findings support the feasibility of a larger randomized trial. ClinicalTrials.gov Identifier: NCT04804579.

摘要

酒精会增加 HIV 感染者(PLWH)跌倒的风险,但针对有饮酒问题的 HIV 感染者的跌倒预防试验却很缺乏。本研究旨在评估针对有饮酒问题的 PLWH 开展为期 10 周的在线跌倒预防干预措施的随机对照试验的可行性,该干预措施包括每周虚拟小组讨论、个人电话检查和家庭锻炼。在符合条件的人群中,有 53.5%(23/43)的人入组(12 人入组干预组,11 人入组对照组)。参与者的平均年龄为 58 岁;82.6%的人在过去 6 个月中有跌倒经历;65.2%的人有酒精使用障碍;95.7%的人完成了干预后的评估。该干预措施的评价非常高(客户满意度问卷-8 评分为 30.4, = 1.6),且小组和个人电话会议的出席率也很高。初步分析表明,该干预措施可能降低跌倒和饮酒频率的发生几率。研究结果支持开展更大规模的随机试验。临床试验注册编号:NCT04804579。

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