Department of Oral Medicine and Radiology, Darshan Dental College and Hospital, Loyara, Udaipur, Rajasthan, India.
Department of Oral Medicine and Radiology, Sankalchand Patel University, Visnagar, Gujarat, India.
J Cancer Res Ther. 2024 Jan 1;20(1):441-444. doi: 10.4103/jcrt.jcrt_1757_22. Epub 2023 Apr 7.
Fibro-osseous lesions (FOLs) of the craniomaxillofacial region comprise a group of developmental, dysplastic, and neoplastic alterations. FOLs include ossifying fibromas (OF), cemento-ossifying fibroma (COF), familial gigantiform cementoma (FGC), fibrous dysplasia (FD), and cemento-osseous dysplasia (COD). Evidence suggests that some FOL, especially FD and OF may have a risk of spontaneous malignant transformation. This report documents a rare case of malignant transformation of ossifying fibromas of the jaw and the probable cause for same. Although it is rare, the clinician should have a complete follow up to observe such changes among the patients having FOLs.
颅面纤维骨病变（FOL）包括一组发育性、发育不良性和肿瘤性改变。FOL 包括骨化纤维瘤（OF）、骨化性纤维瘤（COF）、家族性巨细胞牙骨质瘤（FGC）、纤维结构不良（FD）和骨化性牙骨质发育不良（COD）。有证据表明，一些 FOL，特别是 FD 和 OF，可能有自发恶性转化的风险。本报告记录了一例颌骨骨化纤维瘤恶变的罕见病例及其可能的原因。虽然这种情况很少见，但临床医生应该对患有 FOL 的患者进行全面随访，以观察这些变化。
