Department of Physiology, Semmelweis University School of Medicine, Budapest, Hungary.
HUN-REN-SU Inflammation Physiology Research Group, Hungarian Research Network and Semmelweis University , Budapest, Hungary.
J Exp Med. 2024 May 6;221(5). doi: 10.1084/jem.20240229. Epub 2024 Apr 1.
Pustular psoriasis is an inflammatory skin disease with features of neutrophil-mediated sterile autoinflammation. In this issue of JEM, Baldo et al. (https://doi.org/10.1084/jem.20231464) show that this autoinflammation is driven by a vicious cycle through neutrophil-derived IL-26.
脓疱型银屑病是一种炎症性皮肤病,具有中性粒细胞介导的无菌性自身炎症的特征。在本期《JEM》中,Baldo 等人(https://doi.org/10.1084/jem.20231464)表明,这种自身炎症是由中性粒细胞衍生的白细胞介素 26 驱动的恶性循环引起的。