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干燥综合征患者的多学科治疗方法:一项三年随访研究

Multidisciplinary Therapeutic Approach of a Patient With Sjogren's Syndrome: A Three-Year Follow-Up Study.

作者信息

Kokoti Maria, Zisis Vasileios, Andreadis Dimitrios, Bakopoulou Athina

机构信息

Prosthodontics, School of Dentistry, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, GRC.

Oral Medicine/Pathology, School of Dentistry, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, GRC.

出版信息

Cureus. 2024 Feb 28;16(2):e55148. doi: 10.7759/cureus.55148. eCollection 2024 Feb.

Abstract

Sjögren's syndrome is a chronic, inflammatory autoimmune disorder characterized by lymphocyte infiltration of the exocrine glands. Notably, the rehabilitation of partially edentulous patients with Sjögren's syndrome is limited by the scarce availability of studies that could inform therapeutic modalities and potential challenges during clinical procedures. This case report aimed to present the oral rehabilitation of a patient with Sjögren's syndrome who received fixed partial dentures (FPDs). A 28-year-old female patient sought treatment to restore her missing teeth. She was diagnosed with Sjögren's syndrome by a rheumatologist adhering to the revised version of the European criteria proposed by the American-European Consensus Group and was on a medication regimen including prednisolone, hydroxychloroquine, pantoprazole, pilocarpine, and tear substitutes to manage her condition. The final treatment plan consisted of extractions, management of gingivitis, post-and-core restorations, and a 2 mm vertical dimension increase with the placement of 15 porcelain-fused-to-metal (PFM) crowns and 4 short-span bridges. The patient underwent regular clinical and radiographic evaluations every 3 months since June 2020. Throughout this period, the fixed prostheses, teeth, and periodontal tissues demonstrated remarkable stability and exhibited no complications. This three-year case study provides evidence that meticulous planning and clinical execution can facilitate successful oral rehabilitation in young edentulous patients with Sjögren's syndrome. Tooth-supported fixed prostheses can effectively restore oral function and aesthetic appeal in these individuals, provided they undergo more frequent dental examinations than the general population and maintain a cooperative attitude throughout the treatment process.

摘要

干燥综合征是一种慢性炎症性自身免疫性疾病,其特征为外分泌腺淋巴细胞浸润。值得注意的是,针对患有干燥综合征的部分牙列缺损患者的修复治疗受到限制,因为缺乏能够为治疗方式及临床操作中潜在挑战提供依据的研究。本病例报告旨在介绍一名接受固定局部义齿(FPD)修复的干燥综合征患者的口腔修复情况。一名28岁女性患者因牙齿缺失寻求治疗。她被风湿病学家根据美国-欧洲共识小组提出的欧洲标准修订版诊断为干燥综合征,并正在接受包括泼尼松龙、羟氯喹、泮托拉唑、毛果芸香碱和人工泪液替代品在内的药物治疗方案来控制病情。最终治疗方案包括拔牙、牙龈炎治疗、桩核修复,以及通过安装15颗烤瓷熔附金属(PFM)全冠和4个短跨度桥体使垂直距离增加2毫米。自2020年6月起患者每3个月接受一次常规临床和影像学评估。在此期间,固定修复体、牙齿和牙周组织表现出显著的稳定性,未出现并发症。这项为期三年的病例研究表明,精心规划和临床实施能够促进年轻的牙列缺损干燥综合征患者的成功口腔修复。对于这些患者,牙支持式固定修复体能够有效恢复口腔功能及美观,前提是他们要比普通人群更频繁地接受牙科检查,并在整个治疗过程中保持配合态度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0404/10979817/f457a9abf808/cureus-0016-00000055148-i01.jpg

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