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舍格伦综合征患者的种植体支持式覆盖义齿:一项多中心前瞻性队列研究。

Implant supported overdentures in Sjögren's disease patients: a multicentre prospective cohort study.

机构信息

Department of Maxillofacial Surgery and Oral Pathology, Amsterdam UMC, Vrije Universiteit Amsterdam, The Netherlands.

Department of Oral and Maxillofacial Surgery, Prosthodontics and Special Dental Care, University Medical Center Utrecht, The Netherlands.

出版信息

Clin Exp Rheumatol. 2023 Dec;41(12):2418-2427. doi: 10.55563/clinexprheumatol/cryfka. Epub 2023 Nov 27.

Abstract

OBJECTIVES

To prospectively investigate patient-reported outcomes and clinical performance of implant supported overdentures in edentulous Sjögren's disease (SjD) patients compared to subjects without SjD.

METHODS

51 implants were placed in 12 patients with SjD and 50 implants in 12 non-SjD patients to support overdentures. Clinical performance, marginal bone-level changes, patient satisfaction and oral health related quality of life (OHRQoL) were assessed at 1 (T1), 6 (T6), 12 (T12) and 18 (T18) months after placement of the overdenture. Patient satisfaction, ability to chew and OHRQoL were assessed with validated questionnaires. Marginal bone-level changes were measured on standardised dental radiographs. Clinical parameters included implant and overdenture survival, plaque, bleeding and gingival indices, and probing depth.

RESULTS

OHRQoL in patients with SjD improved significantly after placement of implant supported overdentures at all measuring moments compared to baseline (p<0.05). Nevertheless, ability to chew tough and hard food was significantly better for non-SjD patients at all timepoints after placement of an implant supported overdenture (p<0.05). Implant survival at T18 was 100% in the patients with SjD and 98% in the non-SS group. Mean marginal bone loss at T18 did not differ between patients with SjD and non-SS patients, 1.12±0.74 mm and 1.43±1.66 mm, respectively (p=0.58). Clinical performance was good with no differences between the groups for all outcome measures (p>0.05).

CONCLUSIONS

Implant-supported overdentures have a positive effect on OHRQoL and dental implants can be successfully applied in edentulous patients with SjD with nearly similar outcomes as in non-SjD subjects.

摘要

目的

前瞻性研究比较干燥综合征(SjD)患者和非 SjD 患者无牙颌中种植体支持覆盖义齿的患者报告结局和临床效果。

方法

将 51 枚种植体植入 12 例 SjD 患者和 50 枚种植体植入 12 例非 SjD 患者,以支持覆盖义齿。在覆盖义齿放置后 1(T1)、6(T6)、12(T12)和 18(T18)个月时,评估临床效果、边缘骨水平变化、患者满意度和口腔健康相关生活质量(OHRQoL)。使用经过验证的问卷评估患者满意度、咀嚼能力和 OHRQoL。在标准牙科 X 光片上测量边缘骨水平变化。临床参数包括种植体和覆盖义齿的存活率、菌斑、出血和牙龈指数以及探诊深度。

结果

与基线相比,SjD 患者在放置种植体支持覆盖义齿后所有测量时刻的 OHRQoL 均显著改善(p<0.05)。然而,在放置种植体支持覆盖义齿后所有时间点,非 SjD 患者咀嚼坚硬食物的能力均显著优于 SjD 患者(p<0.05)。在 SjD 患者中,T18 时的种植体存活率为 100%,在非 SS 组中为 98%。T18 时 SjD 患者和非 SS 患者的平均边缘骨损失无差异,分别为 1.12±0.74mm 和 1.43±1.66mm(p=0.58)。临床效果良好,两组间所有结果测量均无差异(p>0.05)。

结论

种植体支持覆盖义齿对 OHRQoL 有积极影响,并且在 SjD 无牙颌患者中可以成功应用种植体,其结果与非 SjD 患者相似。

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