Seale N S, Thrash W J
J Dent Res. 1985 Mar;64(3):457-61. doi: 10.1177/00220345850640031401.
Various treatment variables associated with a standard bleaching technique were systematically recorded in 53 individuals exhibiting intrinsic discoloration of permanent teeth. These variables (predictors) included: (1) etiology (fluoride or tetracycline); (2) age of the patient; (3) the presented color of the stain; (4) the intensity of that color; (5) a long versus short bleaching time technique; and (6) the number of bleaching sessions. These were assessed as to their relationship with the results of treatment (dependent variable). The findings of a multiple regression analysis revealed that the contributions of the individual predictors were significantly different between those stains caused by tetracycline ingestion (N = 27) and those stains due to fluoride ingestion (N = 20). The analysis also revealed that those variables contributing to a significant proportion of the variance in results of treatment when tetracycline was the cause were: (1) the color of the stain and (2) the number of bleaching sessions. When fluoride was apparently the causal agent: (1) the bleaching time technique; (2) age of the patient; (3) color of the stain; and (4) the number of bleaching sessions contributed to a significant proportion of the variance in the results of treatment.
在53名患有恒牙内源性变色的个体中，系统记录了与标准漂白技术相关的各种治疗变量。这些变量（预测因素）包括：（1）病因（氟或四环素）；（2）患者年龄；（3）污渍呈现的颜色；（4）该颜色的强度；（5）长漂白时间技术与短漂白时间技术；以及（6）漂白疗程数。评估了这些变量与治疗结果（因变量）之间的关系。多元回归分析的结果显示，在因摄入四环素导致的污渍（N = 27）和因摄入氟导致的污渍（N = 20）之间，各个预测因素的贡献存在显著差异。分析还显示，当四环素是病因时，对治疗结果方差有显著贡献的变量为：（1）污渍颜色和（2）漂白疗程数。当氟显然是致病因素时：（1）漂白时间技术；（2）患者年龄；（3）污渍颜色；以及（4）漂白疗程数对治疗结果的方差有显著贡献。
