单肺移植后特发性肺纤维化患者的呼吸振荡法与CT图像分析
Respiratory oscillometry with CT image analysis in idiopathic pulmonary fibrosis following single lung transplant.
作者信息
Wu Joyce K Y, Xu Jessica Jia-Ni, Vasileva Anastasiia, Nohra Cynthia, Binnie Matthew, Shapera Shane, Fisher Jolene H, Ryan Clodagh M, McInnis Micheal, Hantos Zoltán, Chow Chung-Wai
机构信息
Division of Respirology, Department of Medicine, University of Toronto, Toronto, Canada.
Toronto General-Pulmonary Function Laboratory, University Health Network, Toronto, Canada.
出版信息
Respir Med Case Rep. 2024 Mar 22;49:102016. doi: 10.1016/j.rmcr.2024.102016. eCollection 2024.
Oscillometry is an emerging pulmonary function testing tool that is conducted during tidal breaths with minimal patient effort. It is highly sensitive to changes in lung mechanics. Oscillometry was recently shown to be highly associated with disease severity in idiopathic pulmonary fibrosis (IPF). The usefulness of oscillometry after single lung transplant in IPF patients is not well understood. Our study demonstrated that oscillometry can detect changes in the graft despite presence of a native fibrotic lung to provide useful information to complement spirometry.
振荡法是一种新兴的肺功能检测工具，在潮式呼吸过程中进行，患者只需付出最小的努力。它对肺力学变化高度敏感。最近研究表明，振荡法与特发性肺纤维化（IPF）的疾病严重程度高度相关。IPF患者单肺移植后振荡法的实用性尚未得到充分了解。我们的研究表明，尽管存在天然纤维化肺，振荡法仍可检测到移植肺的变化，从而提供有用信息以补充肺量计检测结果。
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