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The characteristics and significance of sulfonamides as substrates for Escherichia coli dihydropteroate synthase.

作者信息

Roland S, Ferone R, Harvey R J, Styles V L, Morrison R W

出版信息

J Biol Chem. 1979 Oct 25;254(20):10337-45.

PMID:385600
Abstract
摘要

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The characteristics and significance of sulfonamides as substrates for Escherichia coli dihydropteroate synthase.
J Biol Chem. 1979 Oct 25;254(20):10337-45.
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Sulfonamide resistance mechanism in Escherichia coli: R plasmids can determine sulfonamide-resistant dihydropteroate synthases.大肠杆菌中的磺胺耐药机制：R质粒可决定对磺胺耐药的二氢蝶酸合酶。
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Inhibition of dihydropteroate synthetase from Escherichia coli by sulfones and sulfonamides.砜类和磺胺类药物对大肠杆菌二氢蝶酸合酶的抑制作用。
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