Patil Sandip, Bhat Pravin
Department of Shalakyatantra, Sumatibhai Shah Ayurved Mahavidyalaya, Hadapsar, Pune, MS, India.
Department of Shalakyatantra, Sumatibhai Shah Ayurved Mahavidyalaya, Hadapsar, Pune, MS, India.
J Ayurveda Integr Med. 2024 Mar-Apr;15(2):100893. doi: 10.1016/j.jaim.2024.100893. Epub 2024 Apr 1.
Otitis externa is an inflammatory and infectious disease that affects the external auditory canal. The term otorrhea refers to the outflow of discharge from the ear which is one of the main symptoms of otitis externa along with inflammation. External ear canal pathology or middle ear illness with tympanic membrane perforation is the etiological factor of otorrhea. Otorrhea is an indication of infection. Antimicrobial agents are the conventional treatment of various bacterial and fungal infections, but they have impediments such as resistance development, side effects, patient affordability, etc. The Gandhak Rasayana formulation mentioned in the Ayurvedic text can be a good option for the treatment of various infectious diseases. Karnasrava is a type of ear disease referred to as Vata predominant Tridoshaja disease and it is curable. The term Karnasrava signifies discharge from ear and is self-explanatory. Karnasrava consists of a wide spectrum of diseases and can have a near correlation with otitis externa as per signs and symptoms. Gandhak Rasayana exhibited significant antibacterial, antifungal and anti-inflammatory activity in otitis externa. Evaluating its antibacterial and antifungal activity can provide scientific evidence for the study through the present case report. A 31-year-old male patient registered in OPD at Sane Guruji Hospital, Hadapsar, Pune was clinically diagnosed as Karnasrava (Otitis externa) and pus culture positive for Klebsiella species. We started the treatment with Gandhak Rasayana-an Ayurvedic formulation of 250mg two tablets in the morning and evening with lukewarm water for 21 days. The outcome of the treatment was observed as a reduction in Karnashula (otalgia), Karnasrava (ear discharge), Karnakandu (itching), ear blockage and inflammatory changes. Post-treatment culture was negative for the organism. The improvement was noted in Brighton grading scale from grade III to grade I. Gandhak Rasayana showed significant antibacterial activity in the present case. Evaluating its antibacterial, antifungal and anti-inflammatory activity can provide scientific evidence for the study.
外耳道炎是一种影响外耳道的炎症性和感染性疾病。耳漏是指耳内有分泌物流出，它是外耳道炎的主要症状之一，与炎症并存。外耳道病变或伴有鼓膜穿孔的中耳疾病是耳漏的病因。耳漏是感染的一种表现。抗菌药物是治疗各种细菌和真菌感染的传统方法，但它们存在诸如耐药性产生、副作用、患者负担能力等问题。阿育吠陀文献中提到的甘达克拉萨亚纳配方可能是治疗各种传染病的一个不错选择。卡纳斯拉瓦是一种耳部疾病，被称为以风邪为主的三合病，是可治愈的。卡纳斯拉瓦这个术语表示耳内流出物，不言自明。卡纳斯拉瓦包括广泛的疾病种类，根据症状体征，它与外耳道炎有密切关联。甘达克拉萨亚纳在外耳道炎中表现出显著的抗菌、抗真菌和抗炎活性。通过本病例报告评估其抗菌和抗真菌活性可为该研究提供科学依据。一名31岁男性患者在普纳哈达萨尔的萨内古鲁吉医院门诊部登记就诊，临床诊断为卡纳斯拉瓦（外耳道炎），脓液培养显示肺炎克雷伯菌阳性。我们开始用甘达克拉萨亚纳进行治疗，这是一种阿育吠陀配方药物，早晚各服用两片250毫克，用温水送服，持续25天。治疗结果显示卡纳舒拉（耳痛）、卡纳斯拉瓦（耳漏）、卡纳坎杜（瘙痒）、耳堵塞和炎症变化有所减轻。治疗后培养结果显示该病菌呈阴性。在布莱顿分级量表中，病情从三级改善到了一级。在本病例中，甘达克拉萨亚纳显示出显著的抗菌活性。评估其抗菌、抗真菌和抗炎活性可为该研究提供科学依据。
