Region Västra Götaland, Sahlgrenska University Hospital, Department of Ophthalmology, Mölndal, Sweden.
Region Västra Götaland, Sahlgrenska University Hospital, Department of Ophthalmology, Mölndal, Sweden; Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Acta Derm Venereol. 2024 Apr 2;104:15765. doi: 10.2340/actadv.v104.15765.
The Department of Ophthalmology, Sahlgrenska University Hospital, has until recently been the only eye clinic in the Nordic countries to perform Mohs' micrographic surgery of basal cell carcinoma. This has led to the practice of only the most complicated basal cell carcinomas being operated on with this technique. The purpose of this study was to present the results of these surgeries in patients with at least 5 years of follow-up. A retrospective study of all patients operated upon in 2010-2015 was performed. Data were gathered from their medical charts. Primary outcome was recurrence of basal cell carcinoma. One-hundred and sixty-seven patients were operated on. Mohs' micrographic surgery was used for tumours that were judged as highly aggressive on preoperative biopsy, had ill-defined borders, had recurred after previous surgery, or a combination of these factors. Nine recurrences (5.4% of all radical Mohs' micrographic surgeries) were diagnosed after a mean postoperative time of 37 months (4-84 months). Interestingly, all of these 9 recurrences after Mohs' micrographic surgery were in patients who had such surgery because of a recurrent basal cell carcinoma to start with. Good results can be achieved when operating on the most complicated periocular basal cell carcinomas with Mohs' micrographic surgery but special care has to be taken to ensure radical borders when operating on recurring basal cell carcinomas.
莎翁大学医院眼科系直到最近一直是北欧国家唯一一家开展 Mohs 显微外科手术治疗基底细胞癌的眼科诊所。这导致只有最复杂的基底细胞癌才采用这种技术进行手术。本研究的目的是报告至少随访 5 年的这些手术患者的结果。对 2010 年至 2015 年间进行的所有手术患者进行了回顾性研究。从他们的病历中收集数据。主要结果是基底细胞癌的复发。共对 167 例患者进行了手术。Mohs 显微外科手术用于术前活检判断为高度侵袭性、边界不清、先前手术后复发或这些因素结合的肿瘤。9 例（所有根治性 Mohs 显微外科手术的 5.4%）在术后平均 37 个月（4-84 个月）后诊断为复发。有趣的是，Mohs 显微外科手术后的这 9 例复发均发生在最初因基底细胞癌复发而接受 Mohs 显微外科手术的患者中。对于最复杂的眼周基底细胞癌，Mohs 显微外科手术可以取得良好的效果，但对于复发性基底细胞癌，在手术时必须特别注意确保切缘彻底。
